American journal of physiology . amount ofblood contained in the cannula was never more than 4 During the ex-periment numerous recoveries from fibrillary contractions were observed, andrecords secured during the process of recovery. (Fig. 5.) The above experiment makes evident the fact that under very lowblood-pressure the unloaded heart may be made to beat for a longtime by feeding it through the coronary veins alone. Endocardiac Nutrition of the Heart. 99 IV. The Importance of Nutrition through the Vessels OF Thebesius and the Coronary Veins in Certain Pathological States of the Heart.
American journal of physiology . amount ofblood contained in the cannula was never more than 4 During the ex-periment numerous recoveries from fibrillary contractions were observed, andrecords secured during the process of recovery. (Fig. 5.) The above experiment makes evident the fact that under very lowblood-pressure the unloaded heart may be made to beat for a longtime by feeding it through the coronary veins alone. Endocardiac Nutrition of the Heart. 99 IV. The Importance of Nutrition through the Vessels OF Thebesius and the Coronary Veins in Certain Pathological States of the Heart. There are three pathological states upon which the modes ofnutrition under discussion appear to have an important bearing;namely, fibrillary contractions, arrest of the heart without fibrillation,and arterio-sclerosis of the coronary arteries. The recovery of the cats heart from fibrillary contractions hasalready been mentioned in the description of my experiments ofApril I and June 26. In one of these the heart was fed from the. Figure 5. Curve drawn immediately after marlied fibrillary contractions, by an ordinarymuscle lever attached to the apex of a cats heart fed through the coronary sinus,June 26, 1897. The fibrillation took place one hour after excision of the heart, andlasted two minutes. The lower curve marks the time in seconds. ventricle through the vessels of Thebesius; in the other, from thecoronary sinus through the coronary veins. It is probable thatnutrition through these channels is of great value to the strugglingheart, both in preventing fibrillation, and possibly in recovering theheart after fibrillation has set in. That such a recovery may occur,even in the dog, has recently been demonstrated by MacWilliam ^^ MacWilliam: Journ. of Physiology, 1887, viii, p. 299. loo F. H. Pratt. and Porter.^ There is therefore no ground for denying the possi-bility of recovery in the human heart, although it is likely enoughthat such instances are extraordinarily rare; and
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