. Contributions from the Department of Neurology and the Laboratory of Neuropathology (reprints). ction, thetumor was found to be smooth, slightly dark-er than the brain substance and was mottledby dark areas apparently due to hemorrhageinto the substance of the tumor. Sections were made from various parts ofthe tumor. Those from the posterior por-tion of the tumor showed a cellular aggre-gation of mononuclear cells, irregularly ar-ranged and not enclosed in trabeculse. Thecells were large and the nuclei stained deepblue, the protoplasm pink. Sections from themiddle portion of the tumor showed


. Contributions from the Department of Neurology and the Laboratory of Neuropathology (reprints). ction, thetumor was found to be smooth, slightly dark-er than the brain substance and was mottledby dark areas apparently due to hemorrhageinto the substance of the tumor. Sections were made from various parts ofthe tumor. Those from the posterior por-tion of the tumor showed a cellular aggre-gation of mononuclear cells, irregularly ar-ranged and not enclosed in trabeculse. Thecells were large and the nuclei stained deepblue, the protoplasm pink. Sections from themiddle portion of the tumor showed a some-V hat different appearance in that the- sectionswere traversed by blood vessels. In sectionsfrom the anterior part of the tumor the cellswere surrounded by fibrous bands formingtrabecule. Sections from other portions of thetumor showed this same arrangement, thoughin places the cells showed a disposition to In-filtrate the stroma in a way which suggestedthe appearance of carcinoma. The cells hadthe appearance of the normal pituitary body. Sections from the isolated tumor were stud- -3. Showing uuiHir in n-gitni of ilie litnitaiy Imdy. led by Professor A. J. Sniilh who kindly fur-nished the following report: — The sections show over the surface a thinfibrous capsule, and internally it consisted ofa delicate stroma bearing numerous compara-tively thin-v ailed blood vessels. The stromais covered by the essential cells of the looser places there is a papilliform appear-ance, and in other places there is an appear-ance suggesting an adenocarcinoma. In stillother fields there are large irregular spaces,filled with disintegrated blood. Fibrin andblood pigment are noted. In one portion thestroma is condensed into a delicate fibrillarand noncellularized matrix, the precise natureof which is uncertain. The cells of the tumor are of the type of theglandular portion of the hypophysis, varyingin shape from cuboidal to irregular forms dueto varying pressure.


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