Gynaecology for students and practitioners . e ; indeedthere may be great discrepancy in the size of the two tumours. Micro-scopically both the alveolar and diffused types of cancer may be metwith {see Figs. 384, 385), but there is little in their histological featuresto distinguish the secondary from the primary gro^\i:h. In someinstances the amount of connective-tissue stroma found in secondarygrowths is abnormally large and ill-formed, and shows an unusuallystrong tendency to undergo myxomatous degeneration, and tobecome altered by interstitial haemorrhage. There is great difficulty in dete
Gynaecology for students and practitioners . e ; indeedthere may be great discrepancy in the size of the two tumours. Micro-scopically both the alveolar and diffused types of cancer may be metwith {see Figs. 384, 385), but there is little in their histological featuresto distinguish the secondary from the primary gro^\i:h. In someinstances the amount of connective-tissue stroma found in secondarygrowths is abnormally large and ill-formed, and shows an unusuallystrong tendency to undergo myxomatous degeneration, and tobecome altered by interstitial haemorrhage. There is great difficulty in determining the relative frequency ofthe varieties of ovarian cancer just described. Cancerous changes inoriginally benign cysts are much commoner than was formerly sup-posed, as the results of systematic microscopic examination of thesetumours has clearly shown. As a strictly primary disease ovariancancer is very rare ; many instances originally regarded as primary 680 GYNECOLOGY being shown subsequently to be secondary to cancer of some other. Fig. 386. Secondary Ovarian Carcinoma. The primary growth was situated in the pelvic colon. The microscopic appearances are shown in Fig. 387. A, Site of section shown in succeeding Figure. viscus. The obtrusive size of the secondary growth directs attention MALIGNANT EPITHELIAL TUMOURS 681 to it, while the primary growth being small, and giving rise to nourgent symptoms, remains unrecognized. Post-mortem statistics ofcancer show that secondary growths are frequently found in the ovaryafter death in mammary cancer, m stomach-cancer, and in cancer ofthe intestine. But it must be recollected that in such cases the affectionof the ovary is not recognized during life unless the tumour is oflarge size ; consequently the frequency of secondary ovarian cancer, asclinically met with, is probably considerably underestimated. It isprobable that from a clinical standpoint cancerous changes in an
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectgynecology, bookyear1
