. Ciba Foundation conferences on istopes in biochemistry;. Radioactive tracers in biochemistry; Isotopes -- Physiological effect. C) c c I c c Fig. 3. Pathways for the transformation of hexose to a benzene ring. two such units will yield a six-membered ring with ^*C in adjacent positions, while "head to tail" condensation will distribute the label in para positions of the six-membered product. Both possibilities are ruled out by the isotope distribution which was actually observed (Figs. 2 and 3). A mechanism which fits the isotope data, at least qualitatively, and which does not nec


. Ciba Foundation conferences on istopes in biochemistry;. Radioactive tracers in biochemistry; Isotopes -- Physiological effect. C) c c I c c Fig. 3. Pathways for the transformation of hexose to a benzene ring. two such units will yield a six-membered ring with ^*C in adjacent positions, while "head to tail" condensation will distribute the label in para positions of the six-membered product. Both possibilities are ruled out by the isotope distribution which was actually observed (Figs. 2 and 3). A mechanism which fits the isotope data, at least qualitatively, and which does not necessitate the postulation of novel metabolic pathways for glucose, would involve the cyclization. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Ciba Foundation. Philadelphia, Blakiston


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