Transactions of the Royal Society of Edinburgh . sof the mucous membrane, save at thelower part of the duodenum. Experiment 21. Dog that had fasted eighteen hoursgrammes.—3 cc. bile injected intothe duodenum at e (fig. 21), and28 5 cc. castor-oil with 3 cc. bileinjected at o, and again at o. Necropsy.—The oil had ex-tended throughout the wholelength of the small and large in-testine. There was evidence ofprofuse purgative action, but theincreased vascularity of the in-testinal mucous membrane wasslight. Result of Experiments withCastor-Oil.—It stimulates the in-testinal glands, but not the liv


Transactions of the Royal Society of Edinburgh . sof the mucous membrane, save at thelower part of the duodenum. Experiment 21. Dog that had fasted eighteen hoursgrammes.—3 cc. bile injected intothe duodenum at e (fig. 21), and28 5 cc. castor-oil with 3 cc. bileinjected at o, and again at o. Necropsy.—The oil had ex-tended throughout the wholelength of the small and large in-testine. There was evidence ofprofuse purgative action, but theincreased vascularity of the in-testinal mucous membrane wasslight. Result of Experiments withCastor-Oil.—It stimulates the in-testinal glands, but not the liver. It lowers the bile-secretion, probablyindirectly, owing to its action on the intestinal glands. The appearance of theintestinal mucous membrane was in complete harmony with the belief thatcastor-oil is an exceedingly bland purgative. VOL. XXIX. PART I. 2 U Fig. 20.—Secretion of bile before and after cc. of bile injected, into the duodenum at same, with one ounce of castor-oil, given at c,and at c. Weight 245 kilo-. 1234567 8 Fig. 21.—Secretion of bile before and after castor-oil. 3 injected into duodenum at e. The same witb 285 injected at o, and again at o. 166 PROFESSOR RUTHERFORD ON THE


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