. The American journal of roentgenology, radium therapy and nuclear medicine . s are incomplete,owing to a failure to obtain an clinical diagnosis was pelvic tumor 646 Multiple Myeloma of Bones 647 referred for examination of the gastro-intestinal tract with the tentative diag-nosis of malignancy, this being based onthe history of a 40-pound loss in only positive findings at this timewere in connection with the teeth, wherethere were extensive apical abscesses,and an increase in the width of the aorticshadow which we suggested was due tolues. This case entered the hospit
. The American journal of roentgenology, radium therapy and nuclear medicine . s are incomplete,owing to a failure to obtain an clinical diagnosis was pelvic tumor 646 Multiple Myeloma of Bones 647 referred for examination of the gastro-intestinal tract with the tentative diag-nosis of malignancy, this being based onthe history of a 40-pound loss in only positive findings at this timewere in connection with the teeth, wherethere were extensive apical abscesses,and an increase in the width of the aorticshadow which we suggested was due tolues. This case entered the hospital fourmonths later. In the meantime there had Their consistency was usually soft. Onsection the new growth was seen to replacethe marrow, and in many places thegrowth had broken through the cortexand appeared externally as nodules. Thefiat bones, like the sternum and ribs wereflexible, containing very little bond. Inthe case of the sternum, there was almostcomplete absence of calcium, so that thestructure could be cut easily with theordinary shears. In case II, there was a. Fig. 3. Plate i, C.\se III. Fig. 2. Pl.\te 2, Case III. Plate made at the time of the first examination. A Note extensive involvement of the ribs and clavicles, negative report was made, but a careful scrutiny reveals Also note the absence of pulmonary involvement,early lesions. developed severe pains in the back andchest, and the emaciation had progressedrapidly, the total loss of weight at thistime being 70 pounds. The general exam-ination was negative. The special exam-inations revealed a positive roentgen examination demonstrateda widespread bone lesion which was inter-preted as carcinomatosis. A complete autopsy of both cases(II and III) showed that the lesions wereconfined to the osseous system, therebeing numerous tumors of varying sizes. pathological fracture both at the upperend of the humerus and at the lowerthird of the femur. The pathologicaldiagnosis in both cases (II and III) wa
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