. Bacteriology and mycology of foods. Food. HALE TOXICITY COEFFICIENT 175 or any other equal proportion of stock solution and distilled water may be used, as 5+, 100+10, or 1000+100, etc. If the highest stock dilution (1/100,000) is to be used, then the increase should be by 10,000, thus: 10+1 = 1/110,000 10+2=1/120,000 10+3 = 1/130,000, etc. Determination of the Phenol Coefficient Having determined that dilution which gives the same coagulation opacity as the 5 per cent carbohc acid, it is a very simple matter to determine the phenol albumen coagulating coejB&cient by simply dividing t
. Bacteriology and mycology of foods. Food. HALE TOXICITY COEFFICIENT 175 or any other equal proportion of stock solution and distilled water may be used, as 5+, 100+10, or 1000+100, etc. If the highest stock dilution (1/100,000) is to be used, then the increase should be by 10,000, thus: 10+1 = 1/110,000 10+2=1/120,000 10+3 = 1/130,000, etc. Determination of the Phenol Coefficient Having determined that dilution which gives the same coagulation opacity as the 5 per cent carbohc acid, it is a very simple matter to determine the phenol albumen coagulating coejB&cient by simply dividing the strength of the dilution of the disinfectant tested by the phenol dilution (1/20). We conclude by giving the coagulating coefficients of a few disin- fectants: Name of Phenol Coefficient Phenol Copper sulphate. Mercuric chloride. Silver nitrate Alcohol The Hale Toxicity Coefficient of Disinfectants. Hale has attempted in this procedure to establish the toxicity of different substances and to give them a definite numerical relation to other toxic agents. He further proposed that this toxicity coefficient be established for groups of substances having, in general, a similar pharmacological action. The following procedure was proposed for determining the toxicity coefficient of phenol-like compounds: The animal upon which the substance in question is to be tested shall be the white mouse of not less than 15 nor more than 30 gms. weight. The dose is to be calculated per gram of body weight and should, when diluted, equal between and per gram weight; that is, to for a 20-gm. mouse. The diluent is to be dis-. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Tanner, Fred Wilbur, 1888-1957. New York, John Wiley & Sons, Inc. ; [etc. ,et
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