. Ciba Foundation Symposium on Transplantation. Transplantation of organs, tissues, etc. TRANSPLANTATION TOLERANCE AND AGE 143 I 0 3 c 0-2 0-1 00. âIâ 64 62 64 66 6-8 70 72 74 Log. dose administered to infant (AxC57BL)F|hybrids O , ⢠= standard and test suspensions for assay of mouse no. 1295 â¡ , â = standard and test suspensions for assay of mouse Fig. 2. Results of assays of the type illustrated in Fig. i. Spleen index = spleen weight of mouse receiving S or T suspension body weight spleen weight body weight the graph represents an average of two litters. (Data from Michie and Wood
. Ciba Foundation Symposium on Transplantation. Transplantation of organs, tissues, etc. TRANSPLANTATION TOLERANCE AND AGE 143 I 0 3 c 0-2 0-1 00. âIâ 64 62 64 66 6-8 70 72 74 Log. dose administered to infant (AxC57BL)F|hybrids O , ⢠= standard and test suspensions for assay of mouse no. 1295 â¡ , â = standard and test suspensions for assay of mouse Fig. 2. Results of assays of the type illustrated in Fig. i. Spleen index = spleen weight of mouse receiving S or T suspension body weight spleen weight body weight the graph represents an average of two litters. (Data from Michie and Woodruff, 1962.) of mouse receiving B suspension. Each point on Adoptive ittitnunization Enhancement was earlier listed as a possible interpretation of specific unresponsiveness to skin grafts induced by earlier workers in adult mice. This possibility is not formally excluded in our own case. We have, however, been able to narrow the field somewhat by testing for the presence in our graft-bearing mice of an "efferent block", by virtue of which the graft might be enabled to survive in face of a rejection reaction on the part of the host. In such a case, the graft would be unaffected by adoptive immunity conferred by injection of isologous lymphoid cells preimmunized against the skin-donor. If, however, no efferent block exists, as in the case of tolerance, the same procedure would result in rejection of the skin Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Ciba Foundation Symposium on Transplantation (1961 : London, England); Wolstenholme, G. E. W. (Gordon Ethelbert Ward); Cameron, Margaret P. Boston, Little, Brown
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