. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. NARCOSIS AND CELL DIVISION 23 In Figure 5 is summarized the effect on respiration, growth and the derange- ment of cell division brought about by graded concentrations of chloral hydrate between and per cent. These results resemble those obtained with ethyl urethane. Non-linearity of the mass action curve is characteristic. Also a fair correspondence exists between the concentration giving complete growth inhibi- tion ( per cent) and the concentration at which discontinuity of the respiratory inhibition becomes
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. NARCOSIS AND CELL DIVISION 23 In Figure 5 is summarized the effect on respiration, growth and the derange- ment of cell division brought about by graded concentrations of chloral hydrate between and per cent. These results resemble those obtained with ethyl urethane. Non-linearity of the mass action curve is characteristic. Also a fair correspondence exists between the concentration giving complete growth inhibi- tion ( per cent) and the concentration at which discontinuity of the respiratory inhibition becomes apparent ( per cent). Unlike urethane, however, the per- x o (9 O ABERRANT DIVISION FIGURES ZONE of COMPLETE GROWTH INHIBITION. LOG (10 x CONCENTRATION) FIGURE 5. Summary of complete chloral hydrate data. Log (10X £7/7), aberrant divi- sion figures (per cent) and zone of complete growth inhibition plotted against Log (10 X con- centration of chloral hydrate). centage of aberrant nuclear divisions induced by chloral hydrate is never high, the maximum being in the vicinity of 4 per cent. This maximum is not obtained until the cells are exposed to per cent chloral hydrate, or per cent in excess of the concentration at which discontinuity in the respiratory data is expressed. Again, a possible explanation for this may be an overlapping in the inhibition of the activity and resting systems whereupon after a certain concentration is exceeded, both are inhibited simultaneously. That the more sensitive fraction indicated by chloral hydrate represents about 45 per cent of the total respiration (taking the break in the curve as the end point) in contrast to 35 per cent with urethane makes this possibility plausible. The higher value of respiratory inhibition down to the. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illust
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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology
