Materia medica and therapeutics : for physicians and students . fects and uses are similar to those of quinine, as a substi-tute for which they are much used, but the dose is somewhatlarger. * In an able article by J. Marty, entitled, Contribution a Ietude du sulphatede cinchonidine envisage au point de vue physiologique et therapeutique, Bull. Therap., cvi, pp. 395, 445, 1884, the following conclusions are drawn, viz., thatits action varies greatly; that occasionally therapeutic doses may prove toxic; andthat it should be used only in mild cases, and in doses double those of quinine. T
Materia medica and therapeutics : for physicians and students . fects and uses are similar to those of quinine, as a substi-tute for which they are much used, but the dose is somewhatlarger. * In an able article by J. Marty, entitled, Contribution a Ietude du sulphatede cinchonidine envisage au point de vue physiologique et therapeutique, Bull. Therap., cvi, pp. 395, 445, 1884, the following conclusions are drawn, viz., thatits action varies greatly; that occasionally therapeutic doses may prove toxic; andthat it should be used only in mild cases, and in doses double those of quinine. TONICS CORNUS. 153 CORNUS. Cornus florida, or Dogwood {Nat. Ord. Cornacese), is anindigenous tree found in most parts of the United States, andgrowing in the Middle States to the height of from fifteen totwenty feet. Its flowers are remarkable for large four-leavedwhite or pinkish involucres, which appear with us in May. Theofficinal portion is the bark of the root. It occurs in pieces ofvarious sizes, more or less rolled, and of a reddish-gray color. Fig. CORNUS FLORIDA. INVOLUCRE. Its taste is bitter, astringent, and slightly aromatic. It yields itsvirtues to water and alcohol, and contains cornin (cornic acid),resin, tannic and gallic acids, etc. The barks of Cornus sericea,or swamp dogwood, and of Cornus circinata, or round-leaveddogwood, possess analogous properties. Effects and Uses.—Dogwood is deservedly esteemed the bestsubstitute for cinchona among the native astringent bitters. It 154 MATERIA MEDICA NEUROTICS. is somewhat irritant, and not unfrequently disorders the , in powder, gr. xx to 5j; of the fluid extract f5j or more. SALIX. The BARK of Salix alba, the White Willow, and other spe-cies of Salix {Nat. Ord. Salicacese), is ranked among the astrin-gent bitters. It is little employed, however, except in the formof SALiciNUM (salicin, CisHigOy, a glucoside) a neutral principleprepared from the bark of Salix Helix and other species ofSalix, consisti
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