A manual of hygiene and sanitation . out of service byunion with useless haptophores. The increasing immunitycharacterizing immunization depends upon the regenera-tion of an unlimited number of receptors, so that the cellcan provide for the ever-increasing number of haptophoresbrought to it and still have enough receptors remainingto carry on its own nutrition. ^ 1 Medicine, June, 1903, p. 450. DIPHTHERIA ANTITOXIN. 63 Method of Preparing Diphtheria Antitoxin.— Within a comparatively short space of time the antitoxinshave been discovered, tried, and practically adopted bythe medical profession
A manual of hygiene and sanitation . out of service byunion with useless haptophores. The increasing immunitycharacterizing immunization depends upon the regenera-tion of an unlimited number of receptors, so that the cellcan provide for the ever-increasing number of haptophoresbrought to it and still have enough receptors remainingto carry on its own nutrition. ^ 1 Medicine, June, 1903, p. 450. DIPHTHERIA ANTITOXIN. 63 Method of Preparing Diphtheria Antitoxin.— Within a comparatively short space of time the antitoxinshave been discovered, tried, and practically adopted bythe medical profession of the civilized world as a safe andefficient means for the prevention or the alleviation andcure of several of our most dreaded diseases. A shortaccount of the usual method of preparing the antitoxinof diphtheria will, therefore, probably not be uninter-esting. In the first place, it is necessary that the toxin of thedisease should be produced, which is commonly doneby growing the specific organism in peptone-bouillon. Fig. Filter for removing bacteria from fluid culture-media. When this has attained a powerful and definite virulence,as determined by its effect on small animals of knownweight, the organisms are destroyed by some germicide,such as trikresol, or more commonly are removed bycareful filtration from the bouillon which holds thetoxin in solution. A small quantity, say 1 , of the 64 BACTERIOLOGY. filtered bouillon is then injected into a large animal,such as the horse, which should be in good health,and preferably should have been tested previously byinoculations of tuberculin and mallein to eliminate thepossibility of the presence of tuberculosis or animal manifests for a few days the disturbancespeculiar to the disease in question but usually in a minordegree, since the dose was purposely quite small in pro-portion to its weight; as soon as recovery is evidentanother inoculation of an increased dose is made, and soon until experiment shows t
Size: 1398px × 1788px
Photo credit: © The Reading Room / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookcentury1900, bookdecade1900, booksubjecthygiene, bookyear1903
