Light micrograph of Kupffer cells stained with Trypan blue. Kupffer cells are macrophages localised in the lumen of the liver sinusoids and attached to the sinusoidal endothelial cells. Trypan blue is a vital stain that can be used to label macrophages. Circulating Trypan blue is phagocytosed by macrophages and, in the liver, by Kupffer cells, which become stained blue.

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Photo credit: © JOSE CALVO / SCIENCE PHOTO LIBRARY / Alamy / Afripics
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Keywords: -, biological, biology, blue, cell, cells, healthy, hepatocyte, histological, histology, kupffer, kuppfer, light, liver, lm, macrophage, micrograph, microscopy, normal, phagocytosis, sinusoid, trypan