. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . horion and villi is fibrous,having also an excess of spindle-shaped cells. The blood-vessels are all very large, those of the villi as well as most ofthose of the main wall being gorged with blood. The largeblood-vessels of the cord are empty. Within the cavity ofthe amnion scattered throughout the magma there are numer-ous flakes of tissue of the embryo and a great many free cells. No. 200. Ovum, 35 x 25 x 20 mm.; embryo, C. R., 14 mm. Professor Brodel, Baltimo


. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . horion and villi is fibrous,having also an excess of spindle-shaped cells. The blood-vessels are all very large, those of the villi as well as most ofthose of the main wall being gorged with blood. The largeblood-vessels of the cord are empty. Within the cavity ofthe amnion scattered throughout the magma there are numer-ous flakes of tissue of the embryo and a great many free cells. No. 200. Ovum, 35 x 25 x 20 mm.; embryo, C. R., 14 mm. Professor Brodel, Baltimore. The central nervous system is dissociated and maceratedvery much, the form of the brain and spinal cord being lostentirely. The organs are all deformed, the liver in additionbeing necrotic, as it does not stain at all. There is ulcerationof the front of the head, but over the rest of it, in spite of theextensive internal change, the epidermis is intact. The walls of the umbilical vesicle are broken down entirelyand its lumen is filled with a mass of necrotic cells. Theamnion, chorion, and villi are more fibrous than Fig. 200.—Broken embryo within piece of the chorion, showing stumpyarm. Natural size. No. 201. Ovum, 80 x 60 x 50 mm.; embryo, C. R., 20 Brodel, Baltimore. The ovum was received without villi and upon opening itit was found filled with a fluid which had hardened into a 224 MALL. [Vol. XIX. jelly in formalin. The embryo is atrophic, with a necroticmass on top of its head. The fleshy chorion proved when sectioned to be a mixtureof true chorion, villi, blood, fibrin, decidua, blood sinuses, pusand syncytium. The layers are not at all in regular order, andshow all stages of disintegration. The mesoderm of the villiis fibrous and is often invaded by leucocytes and other points the syncytium invades the blood clot and fre-quently maternal blood sinuses are filled with leucocytes andsyncytium.


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Keywords: ., bookcentury1900, bookdecade1900, booksubjectcon, booksubjectfetus