Light micrograph of prostate cancer showing intraluminal eosinophilic crystalloids within the malignant glands. Intraluminal eosinophilic crystalloids


Light micrograph of prostate cancer showing intraluminal eosinophilic crystalloids within the malignant glands. Intraluminal eosinophilic crystalloids are one of the soft (minor) criteria of prostate cancer. They can be needle-shaped, rod-like, polyhedral, triangular, or have irregular brittle shapes. They are associated more frequently with cancer than with benign glands but are not specific for adenocarcinoma. When present, they are usually seen in well-differentiated prostate cancers.


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