. A Reference handbook of the medical sciences embracing the entire range of scientific and practical medicine and allied science . neces-sary connectionbetween the Diagnosis.—Typical cases oflupus erythema-tosus do not pre-sent any greatdifficulty of diag-nosis, but in thevarious stages ofits evolution cer-tain points of re-semblance toother dermatosesmay bo a causeof is especiallythe ease when weare in the pres-ence of an early lesion, covered more or less with scales,and when the atrophic nature of the process is not in evi-dence. Here we must exclude nearly all


. A Reference handbook of the medical sciences embracing the entire range of scientific and practical medicine and allied science . neces-sary connectionbetween the Diagnosis.—Typical cases oflupus erythema-tosus do not pre-sent any greatdifficulty of diag-nosis, but in thevarious stages ofits evolution cer-tain points of re-semblance toother dermatosesmay bo a causeof is especiallythe ease when weare in the pres-ence of an early lesion, covered more or less with scales,and when the atrophic nature of the process is not in evi-dence. Here we must exclude nearly all of the super-ficial scaly diseases before making a diagnosis. The late. Fig. —Lupus Erythematosus of the cht* an extensive fwus of duct; only slight atrophy ol epider lesions, especially those of the face, sometimes offer diffi-culties in diagnosis. Here the patches may at timesresemble those of lupus vulgaris or of syphilis in thetertiary stage. Both these classes require special con-sideration, but the latter is the more important and willtheiefore be taken up first. The late lesion is most often confounded with lupus-vulgaris, especially in those cases in which true tubercles-of lupus vulgaris have developed at some part of thelesion. In these cases the fact that lupus erythematosus-never ulcerates or attacks the deeper tissue, as docs lupus-vulgaris, is perhaps the most iniportant point in differenti-ation; but the patulous sebaceous follicles, the peculiarscale formation, and the appearance of the central atrophyin lupus eiTthematosus, which has little resemblance tothe seals left an extensive lesion of lupus vulg


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