The morphology and evolutional significance of the pineal body : being part I of a contribution to the study of the epiphysis cerebri with an interpretation of the morphological, physiological and clinical evidence . \K. 80 Neuroglia cells in the human pineal l><ly fioniiii, ISSJ; B, according to Dimil rov:i, method). A, :ic- THE PINEAL BODY 167 Krabbe (II)217 studied one hundred human pineal bodies,both male and female, from birth to seven years of age and fromfourteen years to ninety-two years. There was a gap in hissubjects between the ages of seven and fourteen years. Hefound t
The morphology and evolutional significance of the pineal body : being part I of a contribution to the study of the epiphysis cerebri with an interpretation of the morphological, physiological and clinical evidence . \K. 80 Neuroglia cells in the human pineal l><ly fioniiii, ISSJ; B, according to Dimil rov:i, method). A, :ic- THE PINEAL BODY 167 Krabbe (II)217 studied one hundred human pineal bodies,both male and female, from birth to seven years of age and fromfourteen years to ninety-two years. There was a gap in hissubjects between the ages of seven and fourteen years. Hefound two types of cells in the epiphysis: 1) special pineal cellsand 2) neuroglia cells. He thinks the granules in the cells leavethe protoplasm, traverse the intercellular space to enter theblood, lymph, or cerebrospinal fluid, Krabbe does not agreewith Dimitrova92 that the fundamental element of the pineal. a Fig. 81 Cells with granular protoplasm in the pineal body of Bos taurus (Wei-gerts method), according to Dimitrova, 1901. body is neuroglia, for he considers her criteria in distinguishingneuroglia insufficient. He himself never observed muscle fibersin any of the forms which he has studied. Krabbe concludesthat the epiphysis in man shows certain signs of involution,as, for example, concretions, hyperplasia of connective tissue,neuroglial plaques with cysts, and the presence of cells in a stateof disintegration. The involution begins at seven years ofage, but even in the adult the pineal body shows signs of activefunction. The secretory process is manifest in the following 168 FREDERICK TILNEY AND LUTHER F. WARREN manner: 1) basophilic granules in the nuclei; 2) the latter evac-uated into cytoplasm. This process goes on during the entirelife of the individual even into old age. Biondi (12)49 calls attention to the finding of Constant ini71and Galeotti140 of acidophiles in the pineal
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