. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. PHARMACOLOGY OF SLUG AND CRAYFISH HEARTS 501 Eserine A heart was bathed for 20 minutes in a 1:1 million solution of eser- ine, which has only a slight slowing effect; during this time the solution was frequently washed. In this eserinized heart the acetylcholine thresh- old was lowered to 1:100 million (Fig. ID). Diastolic stoppage oc- 1:100 FIG. 1. Ariolimax. A, normal beat at 16° C. B, effect of acetylcholine 1: 10,000,000. C, effect of acetylcholine 1: 50,000. D, effect of acetylcholine 1 :- 100,000,000 on vent
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. PHARMACOLOGY OF SLUG AND CRAYFISH HEARTS 501 Eserine A heart was bathed for 20 minutes in a 1:1 million solution of eser- ine, which has only a slight slowing effect; during this time the solution was frequently washed. In this eserinized heart the acetylcholine thresh- old was lowered to 1:100 million (Fig. ID). Diastolic stoppage oc- 1:100 FIG. 1. Ariolimax. A, normal beat at 16° C. B, effect of acetylcholine 1: 10,000,000. C, effect of acetylcholine 1: 50,000. D, effect of acetylcholine 1 :- 100,000,000 on ventricle treated for 20 minutes with eserine 1: 1,000,000. E, ef- fect of acetylcholine 1: 5,000,000 on ventricle treated for 20 minutes with eserine 1: 1,000,000. curred with acetylcholine 1: 5 million (Fig. IE), that is, with a solution of acetylcholine 100 times more dilute than is necessary for stoppage of an un-eserinized heart. Atr opine Atropine has no effect except in toxic concentration (1: 1000). Af- ter administration of a non-toxic solution of atropine (1: 10,000) or in. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marine Biological Laboratory (Woods Hole, Mass. ); Marine Biological Laboratory (Woods Hole, Mass. ). Annual report 1907/08-1952; Lillie, Frank Rattray, 1870-1947; Moore, Carl Richard, 1892-; Redfield, Alfred Clarence, 1890-1983. Woods Hole, Mass. : Marine Biological Laboratory
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