Gynecological diagnosis and pathology . Fig. 119.—Telangiectatic the large spaces filled with blood in the substance of the tumour. have seen a large blood cyst develop due to hemorrhage into a fibroidfrom the development of perithelioma. Necrobiosis, or Red Degeneration.—This is probably the commonestdegenerative change met with in fibroid tumours. It is at the same timethe one which gives rise to the most characteristic symptoms and physicalsigns. It occurs most frequently during pregnancy, in the puerperium,or about the time of the menopause. Lorrain Smith and Shaw ascribethe c


Gynecological diagnosis and pathology . Fig. 119.—Telangiectatic the large spaces filled with blood in the substance of the tumour. have seen a large blood cyst develop due to hemorrhage into a fibroidfrom the development of perithelioma. Necrobiosis, or Red Degeneration.—This is probably the commonestdegenerative change met with in fibroid tumours. It is at the same timethe one which gives rise to the most characteristic symptoms and physicalsigns. It occurs most frequently during pregnancy, in the puerperium,or about the time of the menopause. Lorrain Smith and Shaw ascribethe change to thrombosis causing retardation of the circulation, whichleads to a production of fat; and the accumulated lipoids have ahemolytic action and favour the staining of the tumour with haemo-globin. The appearance produced is characteristic. The tumour, insteadof presenting the pearly-white colour of the ordinary fibroid, acquires Plate IV. UTERINE FIBROID UNDERGOING NECROBIOSIS OR RED DEGENERATION DEGENERATIVE CHANGES IN FIBROID TUMOURS 121 a pink or deep red purple hue (see Plate IV.). It loses its firmnessand becomes soft. There is a diffusion of blood-pigment throughout thetissue; the individual fibres are degenerated so that their outlines areindistinct, and the nuclei stained faintly or not at all (fig. 120). Inmore advanced eases there is an actual necrosis of the tissue, leading tothe formation of spaces within the tumour filled with degenerated bloodand dtSbris. Such dead tissue may become infected with the bacilluscoli, leading to abscess formation in the tumour. This change is accompanied by definite symptoms. The tumour,formerly painless, becomes painful. On palpation there is marked ^v. o /• II. ? Vi**11 •!..!Ve&vil ?)


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Keywords: ., bookcentury1900, bookdecade1910, booksubjectgynecology, bookyear1