An American text-book of genito-urinary diseases, syphilis and diseases of the skin . ed after precipitation by the addition of hot water to the urine. This deposit of urates comprises the acid urates of sodium, potassium,and ammonium, and is usually amorphous in character, although occasionallyhedgehog crystals of urate of ammonium may be seen in clumps. It is thesecrystals which often form the nucleus of calculi in children. Urates areoften constituents of calculi, and their significance in the urine is often muchthe same as the uric acid itself. The uric acid tends to deposit itself from a


An American text-book of genito-urinary diseases, syphilis and diseases of the skin . ed after precipitation by the addition of hot water to the urine. This deposit of urates comprises the acid urates of sodium, potassium,and ammonium, and is usually amorphous in character, although occasionallyhedgehog crystals of urate of ammonium may be seen in clumps. It is thesecrystals which often form the nucleus of calculi in children. Urates areoften constituents of calculi, and their significance in the urine is often muchthe same as the uric acid itself. The uric acid tends to deposit itself from a normal urine after standing tenor twelve hours ; then it may be seen in crystalline form both with the unaidedeye and with the microscope. The crystals are always colored, but may beof a light-yellow or a deep reddish-brown, or of any color between these twoextremes. The size, shape, and arrangement of the crystals vary greatly, thecommon shapes being pointed oval, lozenge, and dumb-bell crystals; they alltend to arrange themselves in queer kaleidoscopic masses (see Fig. 2). It is. Fig. 2.—Forms of uric acid: 1, rhombic plates; 2, whetstone forms; 3, quadrate forms; 4,5, prolongedinto points ; 6, 8, rosettes; 7, pointed bundles; 9, barrel forms precipitated by adding hydrochloric acidto urine. this strong tendency to combine in masses which makes uric-acid calculi socommon. Uric acid in excess, then, is found in the system in any condition whichinterferes with perfect oxidation of tissue. Such conditions are commonlycertain affections of the nervous system resulting from mental or physicalexhaustion ; anemias ; chronic gastric diseases ; some acute febrile diseases ;gout and rheumatism. People who are large eaters and take too littlehabitual exercise often have an excess of uric acid in their system. Of course, in attempting to treat such conditions the cause must be foundand treated. In acute rheumatic conditions we find no increase, and often-times even a decrease, of uric


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Keywords: ., bookcentury1800, bookdecade1890, booksubject, booksubjectsyphilis