An American text-book of genito-urinary diseases, syphilis and diseases of the skin . rmal. The papillae of the corium contain a moderate number 914 INFLAMMA TIONS. of small round-cells with a few plasma-cells and mastzellen, and are slightlyswollen. The hair-follicles are the seat of an abundant round-celled infiltra-tion, which surrounds them throughout their entire length, while within thefollicles is a mass of cornified epithelium which projects from the center ofthe papule forming the follicular spine. This spine is produced by the in-creased keratinization of the epithelial wall of the i
An American text-book of genito-urinary diseases, syphilis and diseases of the skin . rmal. The papillae of the corium contain a moderate number 914 INFLAMMA TIONS. of small round-cells with a few plasma-cells and mastzellen, and are slightlyswollen. The hair-follicles are the seat of an abundant round-celled infiltra-tion, which surrounds them throughout their entire length, while within thefollicles is a mass of cornified epithelium which projects from the center ofthe papule forming the follicular spine. This spine is produced by the in-creased keratinization of the epithelial wall of the infundibulum of the fol-licular duct (Jacquet). About the mouths of the sweat-ducts are found simi-lar but less marked changes (Fig. 242). Unna has very clearly pointed outthe histological differences which exist between pityriasis rubra pilaris andlichen ruber :. in the former the cells of the rete are larger than normal, butthere is no loss of the prickles nor colloid degeneration of the epithelium, asin the latter, while the round-celled infiltration of the papillae is much less. Fig. 242.—Section from a patch of pityriasis rubra pilaris : a, thickened corneous layer; b, hypertro-phied rete ; c, hair-follicle ; d, cell-infiltration about follicle ; c, corneous plug in mouth of abundant, and never followed by hyaline degeneration and sclerosis. Theinflammatory changes in pityriasis rubra pilaris are progressive in character,while in lichen they are chiefly regressive. Etiology.—The disease usually begins without known cause in thosewho are otherwise in perfect health. There is no evidence that heredityplays any part either in predisposing to the affection or in directly producingit. Neither age nor sex seems to have any share in its causation. Diagnosis.—When the malady is fully developed there can be but littledifficulty in making the diagnosis: the papulo-squamous lesions situated atthe mouths of the hair-follicles, the abundant scaling of the scalp and face
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Keywords: ., bookcentury1800, bookdecade1890, booksubject, booksubjectsyphilis
