Manual of pathological anatomy . this changein an extreme degree is remarkably altered. It is much smallerthan natural, much paler, and instead of presenting a smooth sur-face, is contracted and puckered so as to resemble, according to aformer observer, *a congeries of little firm globules like thevitellarium of a laying hen. These globular portions areyellowish or bile-stained, and project on the surface; the same areseen on section. They are of various sizes, and evidently consist of parenchy- * Cirrhosis is derived from Ktppos: = orange-coloured or tawny, between red andyellow (Liddell and


Manual of pathological anatomy . this changein an extreme degree is remarkably altered. It is much smallerthan natural, much paler, and instead of presenting a smooth sur-face, is contracted and puckered so as to resemble, according to aformer observer, *a congeries of little firm globules like thevitellarium of a laying hen. These globular portions areyellowish or bile-stained, and project on the surface; the same areseen on section. They are of various sizes, and evidently consist of parenchy- * Cirrhosis is derived from Ktppos: = orange-coloured or tawny, between red andyellow (Liddell and Scott);—from the colour of the degenerated parenchymatousportions. CIRRHOSIS OF THE LIVER. 623 matous substance : they are surrounded, and as it were capsulatedby firm fibroid tissue which extends throughout the whole liver,and gives it a remarkable degree of density and firmness. Thisfibroid tissue is at first highly vascular: it is evidently a newformation, and as such tissue frequently does, contracts and shrinks Fig. Section of liver in a fatty state, with abundant new formed fibrous tissue between the lobules. together, and so draws in the surface at various parts as to pro-duce the irregular nodulated, or *hob-nail condition, as it isfamiliarly termed. The same shrinking also affects the vesselswhich supply the liver: they are surrounded and ensheathed byfibrous tissue in the healthy state, and when this is morbidlythickened and condensed, the pressure exerted upon them narrowstheir channels and materially diminishes the quantity of bloodwhich they are able to convey. Hence the portal current ischecked at its very origin, and the congested capillaries are obligedto relieve themselves by effusion of serum into the peritonealcavity. The capsule of a cirrhotic liver is sometimes smooth,sometimes thickened or attached by adhesions to adjacent parts:these adhesions are often traversed by newly-formed vessels, whichform a kind of collateral circulation between the porta


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Keywords: ., bookcentury1800, bookdecade1870, booksubjectanatomy, booksubjectp