. The American journal of the medical sciences. e recurrentfibroid or fibroplastic tumours, they are oat- or awn-shaped, or made up ofslender, delicate, elongated, nucleated spindle cells. In tlie typical spindle-celled sarcoma, as is shown in Fig. 1, which I drew from a section of atumour of tlie head of the tibia, the cells are thick, and full, and plump,and provided with one or more large nuclei, while their bodies are drawnout at each end into a filamentous process, which is sometimes divided,and renders the cell so large that it may extend over one or two fieldsof the microscope. From the
. The American journal of the medical sciences. e recurrentfibroid or fibroplastic tumours, they are oat- or awn-shaped, or made up ofslender, delicate, elongated, nucleated spindle cells. In tlie typical spindle-celled sarcoma, as is shown in Fig. 1, which I drew from a section of atumour of tlie head of the tibia, the cells are thick, and full, and plump,and provided with one or more large nuclei, while their bodies are drawnout at each end into a filamentous process, which is sometimes divided,and renders the cell so large that it may extend over one or two fieldsof the microscope. From these differences in size a distinction is madebetween the small spindle-celled and the large spindle-celled dimensions of the elements, indeed, appear to exert a most decided in-fluence upon the consistence and prognosis of the growth, since it is pre-cisely tlie small-celled sarcomas that are more liable to be medullary andthe more disposed to recur after extirpation and occasion metastatic depos-its in the internal organs. Fijr. The cellular constituents are separated, and at the same time united, bya more or less abundant hyaline, slightly granular, or, as when the growthshows evidences of a higher degree of development, as happens in thefibrous sarcomas, fibrillated intercellular substance, and they interdigitate,that is to say, the extremity of one cell is received between two contiguouscells, so that a tissue results, which is made of bands or fasciculi of closelyaggregated cells. These bands pursue a parallel course, interlace in everypart of the tumour, or radiate from its centre towards the periphery sothat, on section, groups of what seem to be small round cells, but whichare in reality transverse cuts of fusiform elements, are seen to be surroundedby longitudinal bands of spindle-celled tissue. S[)indle-celled sarcomas are met with as smooth, or slightly nodulated,but rarely bosselated, spherical or ovoid tumours, which are limited by acapsule which is
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Keywords: ., bookcentury1800, bookdecade182, booksubjectmedicine, bookyear1828
