. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 148 RUGH, ET AL. deaths during these first 30 days of life far exceeded the record for the controls, which was Since this study was based upon x-rayed mice which survived embryonic and fetal life, and also the first 30 days of post-natal life, and were studied throughout their life span, the data for weight, skeletal, blood, and cataract changes relate only to the hardiest of the mice exposed in utero. It must therefore be presumed that death of many mice deprived us of further statistical data relating to these physic
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 148 RUGH, ET AL. deaths during these first 30 days of life far exceeded the record for the controls, which was Since this study was based upon x-rayed mice which survived embryonic and fetal life, and also the first 30 days of post-natal life, and were studied throughout their life span, the data for weight, skeletal, blood, and cataract changes relate only to the hardiest of the mice exposed in utero. It must therefore be presumed that death of many mice deprived us of further statistical data relating to these physical variables. The survival of mice selected at one month of age is shown for males and females separately in Figures 1 and 2 during the succeeding 30 months. Note the LD/50 exposures for the various gestation days which kill half of the embryos in utero. These figures (1 and 2) suggest that there is little permanent damage, in terms of life-shortening, when the experimental mice are compared with the controls. The controls are shown in heavy solid lines and those of the various gestation ages receiving different exposures are shown in the other curves. The experimental males did show a slight reduction in survival value, while the difference between the sexes was not at all pronounced in the controls. For the females (Fig. 2) the control curve cuts through the middle of all of the other experimental curves, indicating no effect. Thus, it is evident that those early mouse embryos which. 14 15 16 17 18 MONTHS 19 20~ 2223 ~ 25 26 27~28 ' 29 30 31 SURVIVAL OF FEMALE MICE:LD/50 X-RAYS FROM 0~5 DAYS POST-FERTILIZATION FIGURE 2. The dose of x-rays delivered to female mice on gestation days designated varied with the previously established lethal dose to half of the embryos. Here again the most radiosensitive gestational age, with respect to survival, was the embryo exposed at day after insemination, with 275 r. However, the deviation from the solid control line was not statistical
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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology
