An American text-book of genito-urinary diseases, syphilis and diseases of the skin . Dis., May, 1894. MOLLUSCUM CONTAGIOSUM. 995 to soften and undergo suppuration, the little tumor being thus thrown such cases the central depression is converted into a deeper pocket filledwith pus, and the signs of inflammatory reaction may extend for some dis-tance around each nodule. Very rarely they continue to grow beyond thesize of a pea, and a few instances have been recorded in which a singletumor has attained the size of a small orange (molluscum giganteum). While, as a rule, the lesions are fe
An American text-book of genito-urinary diseases, syphilis and diseases of the skin . Dis., May, 1894. MOLLUSCUM CONTAGIOSUM. 995 to soften and undergo suppuration, the little tumor being thus thrown such cases the central depression is converted into a deeper pocket filledwith pus, and the signs of inflammatory reaction may extend for some dis-tance around each nodule. Very rarely they continue to grow beyond thesize of a pea, and a few instances have been recorded in which a singletumor has attained the size of a small orange (molluscum giganteum). While, as a rule, the lesions are few and scattered, they are occasionallypresent in enormous numbers, and they may be grouped closely together ormay be scattered promiscuously over the whole integument, as no part isexempt except the palms and soles. They have been observed even onmucous membrane. The disease occasions no subjective symptoms, exceptrarely a slight itching. Anatomy and Pathology.—Notwithstanding its clinical unimportance,the disease has given rise to a comparatively extensive literature and been. Fig. 246.—Molluscum contagiosum, showing group of typical molluscum-cells (authors ease, section,and photomicrograph). the occasion of very warm discussions. Dermatologists to-day are by nomeans agreed as to the nature and seat of the pathological changes. Thepeculiar acinous structure of the new growth on vertical section, as well asthe gland-like and sebaceous appearance of the mass when expressed, fur-nished fair foundation for the belief of the earlier writers that the affectionwas a disease of the sebaceous glands. The most elementary of modernhistological methods, however, readily demonstrate the incorrectness of thisview, which, in fact, is maintained to-day only by Kaposi and a few to the vast majority of competent authorities, the disease is a pro-liferation of the epithelial cells of the rete, accompanied, according to some,by degeneration of the protoplasm of the cells—d
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