Diagnostic methods, chemical, bacteriological and microscopical, a text-book for students and practitioners . origin a positive reaction is obtainable. 1 See Frost, Pub. Health Rep., 1912, XXWI, 97; Broers and Smit, Nederl. Tijdschr. , 1915, 11, 1175; also, Hort, Lakin and Banians (Brit. Med. Jour., 1915, _i, 541),Foster (Ibid., 543) and Donaldson (Lancet, 1915, i, 1333), who suggest that the meningococ-cus is only a phase in the life history of the true infective agent. - See Dubois, Jour. Am. Med. Assn., 1913, LX, 820; also, Wollstein, Jour. Exper. Med.,1914, XX, 201; Dubois and Ne


Diagnostic methods, chemical, bacteriological and microscopical, a text-book for students and practitioners . origin a positive reaction is obtainable. 1 See Frost, Pub. Health Rep., 1912, XXWI, 97; Broers and Smit, Nederl. Tijdschr. , 1915, 11, 1175; also, Hort, Lakin and Banians (Brit. Med. Jour., 1915, _i, 541),Foster (Ibid., 543) and Donaldson (Lancet, 1915, i, 1333), who suggest that the meningococ-cus is only a phase in the life history of the true infective agent. - See Dubois, Jour. Am. Med. Assn., 1913, LX, 820; also, Wollstein, Jour. Exper. Med.,1914, XX, 201; Dubois and Neal, Am. Jour. Dis. Child., 1915, IX, i. Collignon and Pilod (Presse med., 1911, XIX, 732) advocate the following test to differ-entiate meningococcic from other types of meningitis. To a few (50 drops) of centrifugedspinal fluid add one to foiu: drops of antimeningococcus serum and incubate the mixture (alongwith a control tube containing only spinal fluid) at 56° C. for 12 hours. If the serum andspinal fluid be homologous, a definite precipitation vnU be observed. This test appears to 684 DIAGNOSTIC METHODS. Tubercular Meningitis. The fluid in such cases is usually clear, but may be slightly cellular elements are largely mononuclear while a few red cells may bepresent. If tubercle bacilli cannot be found after careful search, the presenceof a lymphocytosis along with an increased protein-content will be at least sug-gestive, while animal inoculation or the tuberculin test will clear up the diag-nosis in most cases. (See Lucas^)Acute Anterior Poliomyelitis. This disease has been definitely established as infectious through the workof Flexner and his associates. The causative agent was known to belong tothe ultra-microscopic type and to pass the Berkefeld filter. In other words itis a filterable virus, the point of ingress and egress of which is the nasal andpharyngeal mucosa. This virus is transmitted by means of the biting stable-fly(stomoxys


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