Practical physiological chemistry; a book designed for use in courses in practical physiological chemistry in schools of medicine and of science . 2. Mellanby: Jour, of Physiol., 36, 472, 1908. Wilson: Jour. Biol. Chem., iS, 17, 1914-•Amberg and Morrill: Jour. Biol. Chem., 3, 311, : Jour. Assn, 55, 117S, 1910. 8 Rose: Jour. Biol. Chem., 10, 265, 1911. 9 Folin: Ibid., 11, 253, 1912. 344 PHYSIOLOGICAL CHEMISTRY Hypoxanthine occurs ordinarily in those tissues and fluids whichcontain xanthine. It has been found, unaccompanied by xanthine, inbone marrow and in milk. Unlike xan
Practical physiological chemistry; a book designed for use in courses in practical physiological chemistry in schools of medicine and of science . 2. Mellanby: Jour, of Physiol., 36, 472, 1908. Wilson: Jour. Biol. Chem., iS, 17, 1914-•Amberg and Morrill: Jour. Biol. Chem., 3, 311, : Jour. Assn, 55, 117S, 1910. 8 Rose: Jour. Biol. Chem., 10, 265, 1911. 9 Folin: Ibid., 11, 253, 1912. 344 PHYSIOLOGICAL CHEMISTRY Hypoxanthine occurs ordinarily in those tissues and fluids whichcontain xanthine. It has been found, unaccompanied by xanthine, inbone marrow and in milk. Unlike xanthine it may be easily crystallizedin the form of small, colorless needles. It is readily soluble in alkalis,acids, and boiling water, less soluble in cold water and practically in-soluble in alcohol and ether. The predominating inorganic salt of muscle is potassium this salt we have present chlorides and salts of sodium, calcium,magnesium, and iron. Sulphates are also present in traces. Mendel and Saiki have made some interesting observations upon thechemical composition of non-striated or smooth (involuntary) mammalian. Fig. III.— ter the drawings of Horbaczewski, as represented in Neubauer and Vogel. {Ogden.) muscle, such as the urinary bladder and the muscular coat of the stom-ach of the pig. Hypoxanthine was found to be the predominant purinebase present. Creatine and paralactic acid were also isolated. Theseinvestigators were unable to demonstrate, definitely, the presence ofglycogen in the non-striated muscles studied, but state that thetissues possess the property of transforming glycogen in the char-acteristic enzymatic way. The most important part of their in-vestigation consists in a rather complete analysis of the inorganicconstituents of these muscles. A notable difference in the relativedistribution of the various inorganic constituents was observed, adifference which, according to the authors, can be accounted for inpart only by an
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