Transactions . o frequently ad-vice and relief are sought in the office of the ophthalmologist,migraine. To enumerate the more conmion symptoms hereis needless, but there are certain manifestations which sug-gest a course of events in some cases similar to that of thesecases of transient blindness from circulatory interruption: 804 Langdon: Alternating Transient Monocular Blindness. first, the cases where there have been many attacks ofmigraine with fimctional derangement, hemianesthesia andaphasia especially, which culminated in an attack which didnot clear up but became permanent, closely pa


Transactions . o frequently ad-vice and relief are sought in the office of the ophthalmologist,migraine. To enumerate the more conmion symptoms hereis needless, but there are certain manifestations which sug-gest a course of events in some cases similar to that of thesecases of transient blindness from circulatory interruption: 804 Langdon: Alternating Transient Monocular Blindness. first, the cases where there have been many attacks ofmigraine with fimctional derangement, hemianesthesia andaphasia especially, which culminated in an attack which didnot clear up but became permanent, closely paralleling theperiods of visual loss in the writers patient, and the finalpermanent defect; second, the cases where a typical organiclesion of some portion of the brain has been simulated manytimes—for example, one of Oppenheims where a typicalcerebellar symptom-complex was produced; third, thosecases of transient blindness associated with migraine andtransient diplopia in the same subject, as in the case just. Fig. 3.—Fall in pressure due to injection 3 minims of 1% nitroglycerine. reported, making it seem possible that contraction of differentvessels occurs at different times. As additional evidence, pointing toward spasm ratherthan a drop in blood-pressure as the etiological factor inthese cases, may be considered the therapeutic results inone of Noyess patients: a man blind in both eyes for six-teen hours with typical fundus changes, and who completelyrecovered in twenty minutes following inhalations of amylnitrite, a drug which promptly relaxes capillaries and lowersblood-pressure. Let us now consider briefly the explanation advanced byNettleship and Leber and in a modified form by Loring and Langdon: Alternating Transient Monocular Blindness. 805 Werner. Nettleship and Leber each believed that theabrupt diminution in size of the blood-stream from theinternal carotid to the ophthalmic, as well as the abruptturn made in changing its course, had a decided retardingeffect


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Keywords: ., bookcentury1800, bookdecade1860, booksubjectophthalmology, bookye