. Pathological technique; a practical manual for workers in pathological histology and bacteriology. t usually being two or three times as long as broadand having square or slightly concave ends. These seg-ments represent the bacillus, which is among the largest ofthe bacteria (Fig. 82). Pathogenesis.—Mice, guinea-pigs, and rabbits inoculatedsubcutaneously die with a general invasion of the blood bythe organism. Mice are most susceptible to the infection,dying in about twenty-four hours, while guinea-pigs andrabbits survive longer. In all these animals the most striking lesion is a large softs


. Pathological technique; a practical manual for workers in pathological histology and bacteriology. t usually being two or three times as long as broadand having square or slightly concave ends. These seg-ments represent the bacillus, which is among the largest ofthe bacteria (Fig. 82). Pathogenesis.—Mice, guinea-pigs, and rabbits inoculatedsubcutaneously die with a general invasion of the blood bythe organism. Mice are most susceptible to the infection,dying in about twenty-four hours, while guinea-pigs andrabbits survive longer. In all these animals the most striking lesion is a large softspleen, and in the guinea-pig also an extensive inflammatoryedema of the subcutaneous tissues. On microscopic exam-ination the bacilli will be found in the organs and blood ofthe heart. If the animal has been dead some time, thenumber of bacilli present in these situations will be verygreat, owing to the post-mortem growth. It is characteristic 328 PATHOLOGICAL TECHNIQUE. of the bacillus of anthrax in cover-slip preparations from in-fected tissues that it should have a narrow capsule (Fig. 83).. Fig. 82.—Bacillus of anthrax : portion of a colony three days old upon a gelatinplate; X 1000 (Frankel and Pfeiffer).


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Keywords: ., bookcentury1900, bookdecade1910, bookidpath, booksubjectpathology