. Electronic apparatus for biological research . Figure Arrangements used for measuring microelectrode resistance (c) the membrane electrode and junction potentials. A three-position switch is connected between the input and earth, in which the first position is open, the second connected through a known resistance i?(5-10 MO) to earth, and the third linked directly to earth. The input is connected to each position in turn and the potential differences noted. The electrode resistance is obtained either from the relationship or R. = R K = R (^1-3 - ^2-3) ^2-3 (1^^1-2) iV^- V,-o) Connection
. Electronic apparatus for biological research . Figure Arrangements used for measuring microelectrode resistance (c) the membrane electrode and junction potentials. A three-position switch is connected between the input and earth, in which the first position is open, the second connected through a known resistance i?(5-10 MO) to earth, and the third linked directly to earth. The input is connected to each position in turn and the potential differences noted. The electrode resistance is obtained either from the relationship or R. = R K = R (^1-3 - ^2-3) ^2-3 (1^^1-2) iV^- V,-o) Connection between electrode and amplifier The simplest method of connecting the electrolyte within an electrode to the input of an amplifier is to insert a silver wire previously coated electrolytically with silver chloride. However, a preferable method is to connect the electrode to the metal junction through a Ringer-agar bridge: this will ensure a more stable electrode potential for the Ag-AgCl-electrolyte junction, as the electrode surface can be formed and left in place. The 544
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