Organic and functional nervous diseases; a text-book of neurology . many cases occur of this lasttype which are never recognized as cases of poliomyelitis. *See Epidemic Infantile Paralysis. Starr, Joum. Amer. Med. Assoc, July 11, 1908. PATHOLOGY. 265 Figures 108 to 111 demonstrate the lesions that are found in casesthat succumb soon after the onset. There is a distension of the bloodvessels botn in the meninges and in the gray matter of the spinal cordand many minute hemorrhages in the gray matter. There is an infil-tration of the meninges and of the cord with serum and with emigrat-ing leuco
Organic and functional nervous diseases; a text-book of neurology . many cases occur of this lasttype which are never recognized as cases of poliomyelitis. *See Epidemic Infantile Paralysis. Starr, Joum. Amer. Med. Assoc, July 11, 1908. PATHOLOGY. 265 Figures 108 to 111 demonstrate the lesions that are found in casesthat succumb soon after the onset. There is a distension of the bloodvessels botn in the meninges and in the gray matter of the spinal cordand many minute hemorrhages in the gray matter. There is an infil-tration of the meninges and of the cord with serum and with emigrat-ing leucocytes. The serum fills the lymph spaces about the vesselsand about the nerve cells, the leucocytes infiltrate the tissues every-where, cluster about the cells, and make their way into the the neuroglia there is a great increase of small cells andnuclei which may be so intense as to obscure the other elements. Thedegenerative processes in the ganglion cells or motor neurones appearearly, all varieties of degenerative changes being seen. Fig. Acute poliomyelitis. Death 10 days after onset. Lumbar region. Distension of blood vesselsand absence of motor cells is seen. The serious infiltration obscures the outline of gray matter.(Larkin.) The cell may have a cloudy appearance and be slightly swollen,staining more deeply by reagents, the chromophile granules appearingto be larger than in the normal cells, as seen by the Nissl stain, andthe nucleus appearing granular. This is shown in Plate III., B(page 34). A further stage of degeneration is shown by the fact thatthe protoplasm no longer absorbs stains; the cell is swollen, has lost itssharp outline, has a homogeneous appearance, and the nucleus is faint,as are also the outlines of some of the dendrites. It is probable thatin both these stages of degeneration an arrest of the process and agradual regeneration and a return to the condition of health with re-sumption of the function of the cell is possible. If th
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