. The Alumni journal. College of Pharmacy of the City of New York; Pharmacology. PUBLISHED BY THE ALUMNI ASSOCIATION OF THE COLLEGE OF PHARMACY OF THE CITY OF NEW YORK. Vol. I. New York, February, 1894. No. I. RELATIONSHIP BFTWEEN THE CHEMICAL CONSTITUTION AND THE PHYSI = OLOQICAL ACTION OF THE NEWER SYNTHETIC REHEDIES. Delivered at the meeting of the Alumni Association, January loth, 1894. BY VIRGIL COBLENTZ, , , Professor of Theory and Practice of Pharmacy, Director of the Pharmaceutical Laborator^^ T^O the beginner or even the old stu- dent, the vast array of the organic form
. The Alumni journal. College of Pharmacy of the City of New York; Pharmacology. PUBLISHED BY THE ALUMNI ASSOCIATION OF THE COLLEGE OF PHARMACY OF THE CITY OF NEW YORK. Vol. I. New York, February, 1894. No. I. RELATIONSHIP BFTWEEN THE CHEMICAL CONSTITUTION AND THE PHYSI = OLOQICAL ACTION OF THE NEWER SYNTHETIC REHEDIES. Delivered at the meeting of the Alumni Association, January loth, 1894. BY VIRGIL COBLENTZ, , , Professor of Theory and Practice of Pharmacy, Director of the Pharmaceutical Laborator^^ T^O the beginner or even the old stu- dent, the vast array of the organic formulae presented by the sj^nthetic remedies, is at first confusing. However, owing to the efforts of chemists, the entire structure is built up so systematically,like unto the various parts of a great build- ing, each and every part has its exact position and relationship to the general whole, so that together they unite in forming a uniform and perfect structure. The wonderful combining capacity of carbon gives rise to the infinite number of compounds already known to exist, and even as great a number theoretically possible. The classification of these, among which we have multitudes of isomers is made a simple matter by the use of graphic formulae and a systematic nomenclature ; thus by means of this configuration we are able to express clearly and concisely at a glance, the exact relationship these bodies possess, one to another. Before presenting the subject proper, a general survey of the field is necessary in order that we may arrive at an intelligent understanding of the subject. Methane or marsh-gas CH4 furnishes us the theo- retical source of all carbon compounds, these being derived by the substitution of one or more of its hydrogen atoms by atoms or groups of other elements. These derivatives of methane are classed under the so-called " Paraffin ; On replacing one or more ^ of the hydrogens in methane by the halogens CI., Br. or I. we give rise to H Mo
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