. Pathogenic micro-organisms, including bacteria and Protozoa; a practical manual for students, physicians and health officers. ele-vated, drop-like masses, hav-ing a diameter of 1 to 2 gelatin stick cultures thegelatin is not liquefied. Growth on Agar and BloodSerum.—The colonies appearas small transparent, roundpoints, which have a grayish-yellow color and are slightlyelevated above the surface ofthe medium. Pathogenesis.—Subcu-taneous injections of a cultureof this micrococcus in minutequantity is usually fatal towhite mice. The micrococciare found in comparativelysmall numbers in the


. Pathogenic micro-organisms, including bacteria and Protozoa; a practical manual for students, physicians and health officers. ele-vated, drop-like masses, hav-ing a diameter of 1 to 2 gelatin stick cultures thegelatin is not liquefied. Growth on Agar and BloodSerum.—The colonies appearas small transparent, roundpoints, which have a grayish-yellow color and are slightlyelevated above the surface ofthe medium. Pathogenesis.—Subcu-taneous injections of a cultureof this micrococcus in minutequantity is usually fatal towhite mice. The micrococciare found in comparativelysmall numbers in the blood of the vessels and heart, but aremore numerous in the spleen, lungs, liver, and kidneys. Intraperi-toneal injections given to guinea-pigs and mice are followed bypurulent peritonitis, beautifully formed cocci in groups of fourbeing obtained in immense numbers from the exudate. Rabbits anddogs are not affected by large doses of a culture subcutaneously orintravenously administered. The serum from immunized cases has not been used therapeuticallyin human infection. Vaccines may be employed as with Micrococcus tetragenus from peritoneal fluid. Stainedwith fuchsin. (Fraenkel.) X1000 diameters. THE STREPTOCOCCI. Under this name must be included not only the streptococci whichexcite inflammation in man, but all spherical bacteria which divide,as a rule, in one plane only and remain attached in longer orshorter chains. This name comprises by no means so many varietiesof bacteria as are grouped under the title bacilli. There are,nevertheless, a considerable number of distinct groups of streptococciwhich differ decidedly both in their cultural characteristics and theirpathogenic properties. The streptococci average about 1/^ in diam-eter. None of them forms spores or is motile. They are rathereasily killed by disinfectants. Those that are pathogenic rarely re-produce themselves outside the bodies of man and animals. THE PYOGENIC COCCI. 369 Streptococcus Pyogen


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