. Evolution and disease . Fig. 102.—Clett-lip and nose in a Dog. with a peculiar cleft in its nose. At first we thoughtthat the case was an example of hare-lip, but on makinginquiry we found it to be a distinguishing feature ofthis breed of dogs and that it conferred upon them ahigh money value. The bitch was brought to Bath, andMr. Freeman was successful in crossing her with aSkye-terrier and obtained some pups. Half the litterhad normal noses like the dog, the remainder hadsplit noses and lips like the mother. The pups from TRANSMISSION OF MALFORMA TIONS. 191 this litter have since had young


. Evolution and disease . Fig. 102.—Clett-lip and nose in a Dog. with a peculiar cleft in its nose. At first we thoughtthat the case was an example of hare-lip, but on makinginquiry we found it to be a distinguishing feature ofthis breed of dogs and that it conferred upon them ahigh money value. The bitch was brought to Bath, andMr. Freeman was successful in crossing her with aSkye-terrier and obtained some pups. Half the litterhad normal noses like the dog, the remainder hadsplit noses and lips like the mother. The pups from TRANSMISSION OF MALFORMA TIONS. 191 this litter have since had young with cleft noses, andthe malformation seems to be well established. Thedeformity consists of a median vertical split in theupper lip, extending some distance between the nostrilsand involving the hard palate (fig. 102). The ex-tent to which the bony portion of the palate is in-. FiG. 103.—The hard palate from a Dog witli hare-Up, showingthe extent to which the hard palate is involved. volved may be seen in fig. 103. Apart from its specialinterest the malformation is of value as showing thatdefects, arising from arrested growth during embryoniclife, are transmitted, and this is clearly the case not onlyin connection with the lips, but with the pinna, eye, eye-lids, and many other parts of the body. It now becomes necessary to detail briefly the leading 192 EI ^OL UTION AND DISEASE. facts connected with the development of the mouth inorder to show that we have here to deal with an arrestof development, as well as to show the reason why thecleft in the dogs nose is median, whereas in man andseveral other mammals, in which the deformity hasbeen recognized, the split is, as a rule, lateral. Fortu-nately the admirable researches of Professor Hisremove much of the difficulty which would otherwisehave existed, and the account ofthis embryologist will be closelyfoll


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Keywords: ., bookcentury1800, bookdecade1890, booksubjectabnormalitieshuman