. Diseases of infancy and childhood . se shows the slightest tendency toimprove, and, vice versa, they increase as the inflammatory process growsworse. Pari passu with the polynuclear increase the Fehling reactiondisappears. This point is extremely important, as there are a number ofcases of tubercular meningitis where the tubercle bacillus cannot be foundeven if the antiformin or the Jousset method is used. In these instancesI consider the copper-reducing substance in the cerebrospinal fluid as highlysuggestive of the tubercular nature of the meningitis. The non-reductionof the Fehling soluti


. Diseases of infancy and childhood . se shows the slightest tendency toimprove, and, vice versa, they increase as the inflammatory process growsworse. Pari passu with the polynuclear increase the Fehling reactiondisappears. This point is extremely important, as there are a number ofcases of tubercular meningitis where the tubercle bacillus cannot be foundeven if the antiformin or the Jousset method is used. In these instancesI consider the copper-reducing substance in the cerebrospinal fluid as highlysuggestive of the tubercular nature of the meningitis. The non-reductionof the Fehling solution or the appearance of a violet color change instead,in Kaplans opinion, is signiflcant of the non-tubercular nature of theaffection unless a mixed infection is at hand. In case a double infection isdemonstrated microscopically, the invader that has the upper hand in theinfection usually reflects upon the behavior of the cerebrospinal fluid wittthe Fehling solution. If it is the tubercle bacillus it will reduce; if it is PLATE XXXrX. 4 1 :x rorol)ros|)iiinl INhMiingitis. Aii((i]isy slun\ed a yolI<nvisli-orotMi. miioo-piinilont o\udnti\ clioosy in clmractiM-, ((norinu tho antorior two-iliivdsof the cen-obruiu. Tlio Ihiid obtainod by hunbar inii\otnro ar^ woll as thatby iiitravoiitricuhir aspiration showtnl a ]nno inlluon/.a baiillus. Tlioautopsy was ))orforniod by Dr. John Larkin. The lluid oxaminod by and Dr. M. 1). Kaphm. CEREBRO-SPINAL MENINGITIS. 787 another organism it will. not. Tlio latter plienonieiioii is due to the faet thatit produces a marked increase in the polynuclears, which in some way areresponsible for the non-reduction. The importance of cerebro-spinal fluidexaminations in paediatrics needs no emphasis. Either constipation or diarrhoea may be present. The bladder actswell, although enuresis may exist. In some cases there is a marked retentionof urine. The joints are usually swollen, simulating rheumatism. Thereis also a distinct petechial erupti


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