. Gynecology : . Fig. 52:—Kraurosis Vui/v\ clitoris and labia minora have disappeared. The vulva is white and creased. The vaginais atrophied and stiff at the introitus. This was an extreme case and was inoperable on account ofthe extension of the disease into the orifices of the vagina and urethra. The treatment of advanced cases is vulvectomy, if the process has not in-volved too much vestibule and vaginal introitus. Several cures from ovarian extract have been reported, one of them by theauthor. In this condition ovarian extract theoretically works benefit by itspower to cause hyperemi
. Gynecology : . Fig. 52:—Kraurosis Vui/v\ clitoris and labia minora have disappeared. The vulva is white and creased. The vaginais atrophied and stiff at the introitus. This was an extreme case and was inoperable on account ofthe extension of the disease into the orifices of the vagina and urethra. The treatment of advanced cases is vulvectomy, if the process has not in-volved too much vestibule and vaginal introitus. Several cures from ovarian extract have been reported, one of them by theauthor. In this condition ovarian extract theoretically works benefit by itspower to cause hyperemia of the external genitals and thus improve the circula-tion. Results seem to bear out the theory. 234 GYNECOLOGY. -i \ i-HTF Fig. 53.—-Kraurosis power. On the surface is a thick stratum corneum, under which is the stratum granulosum,much thinner than normal. The line between this layer and the corium is less wavy than usual, dueto poor development of the papillae of the corium. The corium consists of dense connective tissuecontaining few nuclei. Leukoplakia is a somewhat ill-defined disease, similar to kraurosis, butdiffering from it in that it appears in the form of whitish plaques scatteredover the vulvar area rather than a general atrophic process involving the entirevulva. The histologic changes in leukoplakia are more superficial than those ofkraurosis, being located in the epidermis. In kraurosis they are situated in thedermis (Taussig). Leukoplakia may be the seat of a primary cancer of the vulva. Pagets disease occurs rarely in the vulva and may serve as a point of originfor cancer. It is characterized by local irritation, the formation of white blis-ters, thickening of the p
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