Treatise on gynæcology : medical and surgical . Submucous PediculatedFibroid. hidden deformity or a slight infirmity, there are many which are ofmore serious import, and which may lead to conditions resulting indeath. Histogeny.—Velpeau, and after him a number of others, attributedthe development of fibromata to the presence of a blood clot in theuterine The spontaneous organization of coagula after liga-tion of arteries suggested the idea that the same process might result UTERINE FIBROMATA. 217 in the formation of these neoplasms. But experimental study hasdemonstrated that this org
Treatise on gynæcology : medical and surgical . Submucous PediculatedFibroid. hidden deformity or a slight infirmity, there are many which are ofmore serious import, and which may lead to conditions resulting indeath. Histogeny.—Velpeau, and after him a number of others, attributedthe development of fibromata to the presence of a blood clot in theuterine The spontaneous organization of coagula after liga-tion of arteries suggested the idea that the same process might result UTERINE FIBROMATA. 217 in the formation of these neoplasms. But experimental study hasdemonstrated that this organization of coagula is nothing but an in-growth of the elements of the vessel wall, and thus this edifice oftheory, founded on lack of observation, collapses altogether. Klebs2 asserts that these fibrous tumors have their origin in a pro-liferation of the connective tissue and the muscular layers of certainvessels; the different nodules thus formed become aggregated to makeone tumor. Klein wachter describes the evolution of fibromata as due. Fig. 129.—Submucous CEdematous Fibroid with Hypertrophy of Uterine Wall. to a round cell which is found along the capillaries and produces apartial obliteration of them;3 these cells then become fusiform andproduce the nodules. In other words, our knowledge of the subject isstill very imperfect. These neoplasms are very frequent; according to Bayle, who de-scribed certain anatomical features of them in 1813,4 a fifth of allwomen over thirty-five have fibromata. The number is very variable; certain uteri present an enormousnumber of interstitial or pediculated nodules. Most frequentlythere are three or four distinct tumors; at other times there is butone. Though clinically there may appear to be but one, not rarelythere is another in the thickness or on the surface of the organ, 21S CLINICAL AND OPERATIVE GYNAECOLOGY. which either may remain latent indefinitely or may finally develop;this fact is often demonstrated at laparatomies. The
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