. University of Toronto studies. Physiological series. no. 1-98. 1900-28 . Fig. 11. Failure of intestinal dilatation from adrenalin due to paralysis ofthe*mechanism by nicotine. Upper record, response to 2 cc, 1: 100,000 adrenalinbefore nicotine. Lower record, response to 2 cc, 1: 100,000 adrenalin afterinjection of nicotine in the same animal (cat, weight kgm.) Base of bellows20 mm. X 21 mm. (Reduced one-fourth.) [182 LOCATION OF ADRENALIN VASODILATOR MECHANISMS 183 dorsal root ganglia most likely to cause this reaction were those ofthe twelfth and thirteenth thoracic nerves. We have been
. University of Toronto studies. Physiological series. no. 1-98. 1900-28 . Fig. 11. Failure of intestinal dilatation from adrenalin due to paralysis ofthe*mechanism by nicotine. Upper record, response to 2 cc, 1: 100,000 adrenalinbefore nicotine. Lower record, response to 2 cc, 1: 100,000 adrenalin afterinjection of nicotine in the same animal (cat, weight kgm.) Base of bellows20 mm. X 21 mm. (Reduced one-fourth.) [182 LOCATION OF ADRENALIN VASODILATOR MECHANISMS 183 dorsal root ganglia most likely to cause this reaction were those ofthe twelfth and thirteenth thoracic nerves. We have been able toshow that such a mechanism exists, although several of our experi-. Fig. 12. Dilatation of the intestine due to direct application of 1: 1000adrenalin to the superior mesenteric ganglion. Cat. Base of bellows 10 19 mm. (Reduced one-half.) ments gave negative results. We investigated seven animals in all,three dogs and four cats, taking records of the volume changes of aloop of intestine on application of a solution of adrenalin 1: 1000 to theganglia. The preparation of these in the dog was like that described
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