American journal of physiology . 96 192 6 6 6 24 24 3 6 12 24 48 48 48 48 48 48 192 384 384 96 192 12 12 12 12 24 24 48 96 96 384 384 768 384 192 192 192 0 0 0 3 6 6 6 6 0 0 3 6 6 6 6 6 12 24 24 48 24 24 6 12 24 24 24 48 48 24 12 24 48 96 96 48 48 192 192 768 768 768 384 192 12 24 24 48 192 192 96 96 24 24 48 96 192 384 192 192 6 12 24 24 24 48 24 12 24 48 48 96 48 48 270 Arno B. Luckhardt and Frank C. Becht. Days after 4 5 6 7 8 9 10 11121314 13 1017 18 19 20 21 Diln Summary of results obtained by splenectomy. — In every instance thecontrol animals developed the specific anti
American journal of physiology . 96 192 6 6 6 24 24 3 6 12 24 48 48 48 48 48 48 192 384 384 96 192 12 12 12 12 24 24 48 96 96 384 384 768 384 192 192 192 0 0 0 3 6 6 6 6 0 0 3 6 6 6 6 6 12 24 24 48 24 24 6 12 24 24 24 48 48 24 12 24 48 96 96 48 48 192 192 768 768 768 384 192 12 24 24 48 192 192 96 96 24 24 48 96 192 384 192 192 6 12 24 24 24 48 24 12 24 48 48 96 48 48 270 Arno B. Luckhardt and Frank C. Becht. Days after 4 5 6 7 8 9 10 11121314 13 1017 18 19 20 21 Diln Summary of results obtained by splenectomy. — In every instance thecontrol animals developed the specific antibodies more rapidly and inhigher concentration than did the corresponding splenectomized ani-mals. We have plotted composite antibody curA^es of all the asplenic and control animals andfor ready comparison havetransferred them to thesame chart so that themarked difference can beseen at a glance. Fig. 4 shows the com-posite curves of the he-molysins. We call espe-cial attention to thefollowing two points:I. The ultimate concen-. FiGURE 4. — Composite hemolysin curve of 7 con-trol and 8 splenectomized animals, showing markeddifference in the rate of formation and in concen- tration of the hemolvsinstration reached. = 7 control dogs. 8 splenectomized dogs. in the sera of the controlanimals (seven dogs) ismuch higher than in the sera of the splenectomized animals (eightdogs). If the tables are consulted, it will be found that on twenty-seven days the serum of the control animals laked goats corpusclesih a dilution of 1/24,576 or over. On fourteen of the twenty-sevendays the serum of these animals was found to possess lytic action in adilution of 1/98,304 and on eight days was found active in a dilutionof 1/49,152. Comparing these results with the splenectomized ani-mals, we find that on twelve days only was the serum active in a dilu-tion of 1/6144 or over. From the figure we see that the serum of theasplenic animals possessed only one-fourth the titre of the controlsat the hei
Size: 2104px × 1187px
Photo credit: © The Reading Room / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookautho, bookcentury1800, bookdecade1890, booksubjectphysiology
