. Lectures on surgical pathology : delivered at the Royal College of Surgeons of England. lastic fibres, degenerate epithelial cells ofthe air-vesicles or minute bronchi: [h) various and usually degenerateproducts of inflammation from the adjacent parts, granule-cells andmasses, pus-cells, &c.: (c) molecules of calcareous matter, or of pig-ment, and crystals, especially of cholesterine. Such are the ordinary constituents of pulmonary tubercle, and theshrivelled nuclei and imperfect cells, being usually the most abundantand distinct, are called tubercle-corpuscles. Similar materials are foundco
. Lectures on surgical pathology : delivered at the Royal College of Surgeons of England. lastic fibres, degenerate epithelial cells ofthe air-vesicles or minute bronchi: [h) various and usually degenerateproducts of inflammation from the adjacent parts, granule-cells andmasses, pus-cells, &c.: (c) molecules of calcareous matter, or of pig-ment, and crystals, especially of cholesterine. Such are the ordinary constituents of pulmonary tubercle, and theshrivelled nuclei and imperfect cells, being usually the most abundantand distinct, are called tubercle-corpuscles. Similar materials are foundcomposing the tuberculous matter in other parts. In the lungs, accord-ing to Virchow* and Schroeder van der Kolk,f their origin may, in anearlier stage, be traced in changes of the epithelial cells of the air-vesicles. The adjacent copies of the drawings by Schroeder van der Kolk may,with his description of them, suffice to explain the process. The margin of an air-vesicle, from which most of the tubercle-cellsare removed, is shown at a a «; that of another adjacent vesicle, nearly. a- d filled with tubercle-cells, at III; and that of a portion of a third vesi-cle, clear of tubercle-cells, at c. At d the still unaffected wall of theair-vesicle is shown covered with epithelial cells of various sizes, andcontaining nuclei, oil-drops, and granular matter. In the middle andat the end of the same vesicle are some cells of darker tint; they areno longer flat, but filled with some material, and thereby more or less * Wiirzburg Verhandlungen, i, 81. f Over den Oorsprong en de Vorming van Tubercula Puhnonum : Nederlandscli, Lan-cet, 1852. \ Fig. 116. Very thin section of a portion of tuberculous lung, described in the 420 times. 710 TUBERCLES IN THE LUNGS: swollen or spherical; they are epithelial cells more or less distendedwith fluid, and detached, and, as the series of them shows, they con-stantly enlarge. In the next vesicle, h, these cells have become muchlarger, and
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