Induced cell-reproduction and . Fig. 111.—To show the way in which globin is dotted over the surface of an Fig. 112.—To show the scab formed by the application of globin to an ulcer. CLINICAL OBSERVATIONS 345 and when the sore is clean it is once more scarified,and fresh sterile globin is again dotted over itssurface. This procedure can be repeated until theulcer heals. During the scarification it is better todraw blood. Latterly this treatment of ulcers hasbeen improved by using powdered globin (five parts),mixed with two parts (by weight) of kreatin, a mix-ture which produce
Induced cell-reproduction and . Fig. 111.—To show the way in which globin is dotted over the surface of an Fig. 112.—To show the scab formed by the application of globin to an ulcer. CLINICAL OBSERVATIONS 345 and when the sore is clean it is once more scarified,and fresh sterile globin is again dotted over itssurface. This procedure can be repeated until theulcer heals. During the scarification it is better todraw blood. Latterly this treatment of ulcers hasbeen improved by using powdered globin (five parts),mixed with two parts (by weight) of kreatin, a mix-ture which produces more marked proliferation thanpure globin. Many ulcers have now been treated by this method,and we think that we can say safely that it causesmore rapid healing of them than if they were treatedin the usual way. Callous ulcers will usually healby themselves if the limbs are kept at rest, and itwas suggested to us that the cell-proliferation pro-duced by globin was in reality due to the fact that thepatients were kept in bed. This suggestion was dis-proved, however, by the production of extensive pro-liferation in
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