Handbook of meat inspection . ted a normal compositionof the bonea. The coloring material contaiued in the bones wasnot eitracted by water, alcohol, ether, or Chloroform, bnt wasvpadily dissolved in alkalies and dilute acids, especially in KOH andHNO3. lü the first case, a brownish-violet Solution, and in thesecond case, a rose-red Solution was obtained, both of which wereclarified by oxidizing reagents. Onheating, ammonia was developed, and,after calcining, an abundant iron depositremained. Mosselmann, therefore, con-sidered the coloring material as a deri-vative of hemoglobin, and classified


Handbook of meat inspection . ted a normal compositionof the bonea. The coloring material contaiued in the bones wasnot eitracted by water, alcohol, ether, or Chloroform, bnt wasvpadily dissolved in alkalies and dilute acids, especially in KOH andHNO3. lü the first case, a brownish-violet Solution, and in thesecond case, a rose-red Solution was obtained, both of which wereclarified by oxidizing reagents. Onheating, ammonia was developed, and,after calcining, an abundant iron depositremained. Mosselmann, therefore, con-sidered the coloring material as a deri-vative of hemoglobin, and classified itsvith the melanins, which, according toGautier, are insoluble in water, alcohol,and soluble in alkalies and alkalinecarbouates. Judgment.—In a high degree ofochronosis, in which the larger part ofthe skeleton is affected, and-in browncoloration of the skeleton, the decisionis the same as in melanosis. A lessserious case, in which only certain partsof the bones show a daik coloration,is to be considered as iii —, <x Xanthosis of beef. musculature(after Goltz), a, granulär m-terfibrillar pigmcnt. Xanthosis.—A liver-brown discoloration of musculature is occa-sionally observed in cattle. Goltz was the first to call attention tothis changed condition. In the cases which Goltz investigated, theheart, muj^cles of mastication and tongue were most conspicuousfor their dark-brown color. The reraaining portions of the muscu-lature were simply somewhat darker in color than normal. By amicroscopic study, Goltz demonstrated that the peculiar discolora-tion wtiscaused by the presence of yellow granulär pigment betweenthe muscle fibers (Fig. 43). Moreover, the term xanthosis, whichGoltz selected, is quite appropriate for designating the cause of thechanged color. 254 GENERAL PATHOLOGY OF FOOD ANIMALS Wlien tbe pigment is deposited between the fibers, it can berecognized only by a magnification of 300 diameters. Goltz fouudthat it gave neither the reactiou of iron


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