. Preventive medicine and hygiene. of its occurrence in manymembers of the same family. Thus, out of 104 cases of diabetes mellitus22 had a family taint—about 20 per cent. Xaunyn obtained a history ofdiabetes in 35 out of 201 private cases, but in only 7 of 157 hospitalcases. Orthostatic Albuminuria.—Orthostatic albuminuria occurs in boysmore commonly than girls. These are often the children of neuroticparents, and have well-marked vasomotor instability. Defects or pe-culiarities in the filtering apparatus in the kidneys may arise as agerminal variation and be handed on from generation to gene
. Preventive medicine and hygiene. of its occurrence in manymembers of the same family. Thus, out of 104 cases of diabetes mellitus22 had a family taint—about 20 per cent. Xaunyn obtained a history ofdiabetes in 35 out of 201 private cases, but in only 7 of 157 hospitalcases. Orthostatic Albuminuria.—Orthostatic albuminuria occurs in boysmore commonly than girls. These are often the children of neuroticparents, and have well-marked vasomotor instability. Defects or pe-culiarities in the filtering apparatus in the kidneys may arise as agerminal variation and be handed on from generation to conditions which may mean nothing to normal suljjects this defect ^ Davenport, C. B. and Conrad, H. S.: Heredity Fragility of Bone, Acad. Sc, 1915, i, 537. 510 THE HEREDITAEY TEANSMISSIOX OF DISEASE in the kidney may find expression in active disease. In this case, as ingout, it may not be proper to speak of the disease itself being transmitted hereditarily, but the tendency to deviate is so Alcoholism.—Alcohol as well as lead and other poisons can damagethe germ cell of the male in such a way as to express itself by defectiveoffspring. (Eauschkinder, or Jagchildren.) It is a common observation THE HEREDITAEY TEANSMISSION OF DISEASE 511 that among the offspring of drunkards are many cases of unhealthy, in-sane, and criminal types. The disastrous results may be manifested bynervous disorders, varying from hyperexcitability to dementia; or as de-bility and lack of developmental vigor expressed, for instance, in infan-tilism, want of control, imbecility, or as structural abnormalities, espe-cially of the head and brain. The results are so varied, they suggest thatwhat is inherited is general rather than specific. Thus, the offspring ofalcoholic parents are not necessarily predisposed in any one particulardirection, except that the nervous system is most liable to be may be epileptic, idiotic, insane, etc. On the other hand,
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