The human brain : histological and coarse methods of research : a manual for students and asylum medical officers . croscopicexamination, exudation corpuscles, compound cells of Gluge,and other products of inflammation. Such are the conditionsfound in acute hjdrocephalus, distinguishing it from a purelynon-inflammatory form of hydrocephalus, which occurs wherethe fluid, though perhaps slightly tmbicl from broken-downcerebral tissue and shreds from the macerated lining mem-brane of the ventricles, presents no inflammatory materialamongst the debris. 4. Limited Foci of Softening.—Acquaintance wi
The human brain : histological and coarse methods of research : a manual for students and asylum medical officers . croscopicexamination, exudation corpuscles, compound cells of Gluge,and other products of inflammation. Such are the conditionsfound in acute hjdrocephalus, distinguishing it from a purelynon-inflammatory form of hydrocephalus, which occurs wherethe fluid, though perhaps slightly tmbicl from broken-downcerebral tissue and shreds from the macerated lining mem-brane of the ventricles, presents no inflammatory materialamongst the debris. 4. Limited Foci of Softening.—Acquaintance withthe peculiar arrangement of the cerebral blood-vessels soonleads the student to infer that very minute tracts of softening-may result as the effect of thrombosis or embolism, the areainvolved being dependent upon the size of the clot and thesite of its arrest or formation. It is necessary that themechanism of white softening of cerebral tissue, as a result n 2 36 COARSE EXAMINATION OF THE BRAIN. of thrombosis or embolism, be thoroughly imderstood. Theprocess may be best elucidated by the diagram below. a a. Va Fig. 1.—Diagram illustrative of the Effects of Embolic Plugging (after Rindfleisch) .an. Portion deprived of its blood-supply Ijy the embolus. A, Artery. V. Vein filledwith blood-clot. The airows indicate the collateral channels -which lead to a hyperfemiczone around the occluded vessels. Beyond the obstructed artery is the wedge-shaped area ofits distribution, now anfemic and consequently deprived ofits functional power. Below the embolus are seen swollenl)ranches, which tend to establish a collateral circulation. Ifthis fails, we get as a result engorgement of the latter vessels,and a congestive vascular zone surroimding the wedge-shapedarea. The tissue here becomes swollen and oedematous, andminute haemorrhages are apt to occur, whilst the wholecentral and peripheral texture becomes broken up by theeffusion, and a true necrosis occurs of the tissue forming theare
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