. The actinomycetes. Actinomycetales. IIIS'I'OHICAL HAC'KCHOIM) 13 inu; this pc'riod, on \\w inctaholisin of the ;ic- tiiioinycctcs, l)(> work of (Jratia and liis formation of l)a('teriolytie substances by cer- tain actinoniycetes was foHowed by that of Welsch on actinomycetin, a preparation con- taininjj; an enzyme hirj>;ely responsible for this activity. The studies of actinophage l)y aetinomycetes were started w'ith the work of Wiebols and Wieringa. The decomposition of organic materials, ranging from complex substances in the form of plant and animal residues in soil and in composts


. The actinomycetes. Actinomycetales. IIIS'I'OHICAL HAC'KCHOIM) 13 inu; this pc'riod, on \\w inctaholisin of the ;ic- tiiioinycctcs, l)(> work of (Jratia and liis formation of l)a('teriolytie substances by cer- tain actinoniycetes was foHowed by that of Welsch on actinomycetin, a preparation con- taininjj; an enzyme hirj>;ely responsible for this activity. The studies of actinophage l)y aetinomycetes were started w'ith the work of Wiebols and Wieringa. The decomposition of organic materials, ranging from complex substances in the form of plant and animal residues in soil and in composts to pure chemical compounds, in- cluding celluloses, hemicelluloses, proteins, and amino acids, received considerable at- tention, particularly by the writer and his students (Starkey and others). Information was also gradually accumu- lating on the .systematic position and im- portance of act inoiuNcetes in natuial proc- esses. Sex'eral efforts were made to dexclop a system of of ac^tinomycetes thai would take into consideration much of the accumulated information. The earlier in\'(>stigalions on the cultural j)i"operties of aetinomycetes, followed by the studies on their morj)hology, and their aerol)ic and anaeiobic modes of life, led to certain im- jiortant systems of classification. The classi- fication of aetinomycetes in the various edi- tions of Bcrgci/'s Manual was based largely upon cultural, biochemical, and certain mor- phological pi-op(M'ties of the aetinomycetes. It e\entually resulted in a working system of classification, first proposed in 1940, and finally codified (1943) by Waksman and Henrici. The biological period was also character- ized by important contributions to the knowledge o'i pathogenic aetinomycetes, notably the work of Erikson, \on Magnus, Xaeslund, Cope, Rosebury, and others. The strictly parasitic nature of the facultative anaerobic Actirumiyces and some of the. Please note that these images are extracted from scann


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