Diseases of the nervous system : a text-book of neurology and psychiatry . ^ thickening of the pia and arachnoid with lymphocyte andplasma-cell infiltrates. This leptomeningitis varies considerably inits localization, and in its intensity, and the vessels are not infre-quently involved. The whole process closely approaches that of asyphilitic meningitis, but is less intense, and is not accompanied bythe presence of spirocheta. The posterior roots are irregularly atrophied; the sacral and lumbarroots may show not a single unchanged fiber, whereas the cervicalroots are less involved, save in the


Diseases of the nervous system : a text-book of neurology and psychiatry . ^ thickening of the pia and arachnoid with lymphocyte andplasma-cell infiltrates. This leptomeningitis varies considerably inits localization, and in its intensity, and the vessels are not infre-quently involved. The whole process closely approaches that of asyphilitic meningitis, but is less intense, and is not accompanied bythe presence of spirocheta. The posterior roots are irregularly atrophied; the sacral and lumbarroots may show not a single unchanged fiber, whereas the cervicalroots are less involved, save in the case of cervical tabes, where thereverse holds true. The posterior columns show the most uniform lesions. These aregreatly diminished in volume. There is a gradual degeneration, often,however, more intense on one side than the other. The atrophy is. Fig. 294.—Tabetic changes in cord in paresis. not universal, for many fibers are intact. These are usually col-laterals, originating within the cord itself. The direct fibers in thecolumns of Goll and Burdach, from the degenerated posterior roots,are those chiefly involved. A great deal of variability exists as to therespective distribution of the atrophic degenerated fibers; but suchbear a direct proportion to the distribution of the degenerated pos-terior roots. Certain portions of the cord escape, due to anatomicalreasons; these are more particularly the commissural zones, Flechsigscentrum ovale, Gombault and Phillippes triangle in the lumbosacralregion; the cornucommissural zones, Schultzes comma tract and thefascicles of Hoche. (See Plate X.) As a result of the disappearance of the fibers a secondary neurogliainfiltration takes place. This consists of glia with fine prolongations,and also spider cells. In the cases of taboparesis one finds lympho-cytes and plasma cells within t


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