. The basic aspects of radiation effects on living systems. Radiation -- Physiological effect. SENSITIZATION BY OXYGEN 251 period, and later most of them can be easily revived. Mice asphyxiated by nitrogen or carbon dioxide received soft x-rays ( A), at a dose of 1500 r, on the whole body. Whereas the normally irradiated controls all died within 12 days, the animals irradiated during anoxia not only all survived, but subsequently grew at the same rate as the non-irradiated. Fig. 6. Effects of anoxic irradiation on newborn mice. Right to left: 1, Non-irradiated control; 2, irradiated in anox
. The basic aspects of radiation effects on living systems. Radiation -- Physiological effect. SENSITIZATION BY OXYGEN 251 period, and later most of them can be easily revived. Mice asphyxiated by nitrogen or carbon dioxide received soft x-rays ( A), at a dose of 1500 r, on the whole body. Whereas the normally irradiated controls all died within 12 days, the animals irradiated during anoxia not only all survived, but subsequently grew at the same rate as the non-irradiated. Fig. 6. Effects of anoxic irradiation on newborn mice. Right to left: 1, Non-irradiated control; 2, irradiated in anoxia; 3 and 4, normally irradiated. controls. With ultraviolet rays the difference between normal and oxygen-deprived animals was as notable as with x-rays, with reference both to cutaneous lesions (erythema, epidermitis, deep burns) and to general toxic effects (delay in growth, death). Figure 6 shows, starting at the right, a non-irradiated control, an animal irradiated in anoxia (similar in all respects to the control), and two animals normally exposed to the same dose. The last two show severe cutaneous lesions and dis- tortion due to deep edema. The animal at the left died. The same influence of oxygen is found at the other end of the organic scale, in a simple radiochemical reaction such as formation of hydrogen peroxide in water irradiated with x-rays or alpha rays. The primary. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Symposium on Radiobiology (1950 : Oberlin College); Nickson, James J. New York, Wiley
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