. Currents in biochemical research, 1956; twenty-seven essays charting the present course of biochemical research and considering the intimate relationship of biochemistry to medicine, physiology, and biology. Biochemistry -- Research. Fig. 3. Ionic mechanism for the cyclization of squalene to steroids according to Ruzicka (20). presented a comprehensive reaction scheme which connects squalene with the steroids as well as with the various pentacyclic triterpenes, and serves as a highly stimulating working hypoth- esis for future biochemical work (20). According to Ruzicka the cyclization of sq
. Currents in biochemical research, 1956; twenty-seven essays charting the present course of biochemical research and considering the intimate relationship of biochemistry to medicine, physiology, and biology. Biochemistry -- Research. Fig. 3. Ionic mechanism for the cyclization of squalene to steroids according to Ruzicka (20). presented a comprehensive reaction scheme which connects squalene with the steroids as well as with the various pentacyclic triterpenes, and serves as a highly stimulating working hypoth- esis for future biochemical work (20). According to Ruzicka the cyclization of squalene is initiated by a cationic attack at the carbon atom which corresponds to C3 of the steroid skeleton, one of the two positions which are most susceptible to attack by electrophilic reagents. Thereafter, the tetracyclic ring system is 480. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Green, David Ezra, 1910-. New York, Interscience Publishers
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