Clinical lectures on the principles and practice of medicine . res formingthem. 1, A very hard structure, principally formed of fibres (scirrhus).2, A soft structure containing a copious milky fluid, in which numerouscorpuscles swim (encephaloma). 3, A structure having a fibrous basis,so arranged as to form areolae or loculi, which contain a gelatinous gumor glue-like matter [colloid cancer). 3^ *&&< -J:;X~~?%>!-\ Fig. 284. $: t ?• Fig. 285. Q Fig. 283. Fig. 286. 1. Scirrhus presents to the naked eye a whitish or slightly yellowishtinge, is dense and hard to the feel, and offers consider


Clinical lectures on the principles and practice of medicine . res formingthem. 1, A very hard structure, principally formed of fibres (scirrhus).2, A soft structure containing a copious milky fluid, in which numerouscorpuscles swim (encephaloma). 3, A structure having a fibrous basis,so arranged as to form areolae or loculi, which contain a gelatinous gumor glue-like matter [colloid cancer). 3^ *&&< -J:;X~~?%>!-\ Fig. 284. $: t ?• Fig. 285. Q Fig. 283. Fig. 286. 1. Scirrhus presents to the naked eye a whitish or slightly yellowishtinge, is dense and hard to the feel, and offers considerable resistance * See Memoir on Calcification and Ossification of the Testicle, by Mr. J. S. Gam-gee, in Researches on Pathological Anatomy, etc., 8vo. 1856. Fig. 283. Section showing the arrangement of cells and fibres in scirrhus of themamma. Fig. 284. The same, after the addition of acetic acid. Fig. 2S5. Isolated cancer-cells, from the same growth. Fig. 286. The same, after the addition of acetic acid. 250 230 PRINCIPLES OF MEDICINE. to, and often crunches under, the knife. On making a thin section ofthe growth, it is seen to be composed principally of filaments, whichvary in size, and run in different directions, sometimes forming wavedbands, at others an inextricable plexus, among which, however, nucleatedcells (cancer cells) may be seen to be infiltrated. Occasionally thefibrous structure forms loculi or cysts, enclosing similar cells. The so-called cancer-cells may be round, oval, caudate, spindle shaped,oblong, square, heart-shaped, or of various indescribable forms, producedby pressure on their sides. In size they vary from the T75L?th to ths4^pth of an inch in diameter. The cell-wall, when young, is smooth anddistended ; when old, it is more or less corrugated and flaccid. Each cellcontains at least one nucleus, often two, and sometimes as many as commonly there is only one, which is round, or more generally oval,and contains one or two granules or


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Keywords: ., bookcentury1800, bookdecade1870, booksubjectmedicine, bookyear187