. The breast: its anomalies, its diseases, and their treatment . and be somewhat variegated. In some cases the pigment is insufficient in quantity toproduce blackness, when the color may be brown. THE NON-INDIGENOUS TUMORS OF THE MAMMARY GLAND 395 When histologically examined, the tumor is found to be composed of cells thatvary in appearance and in size in different cases. When it is possible to trace the cellsfrom the seat of origin to the deeper tissues they may be large, epithelial in appearance,and extend in prolongations that branch and ramify as in squamous-cell carcinoma,but differing i
. The breast: its anomalies, its diseases, and their treatment . and be somewhat variegated. In some cases the pigment is insufficient in quantity toproduce blackness, when the color may be brown. THE NON-INDIGENOUS TUMORS OF THE MAMMARY GLAND 395 When histologically examined, the tumor is found to be composed of cells thatvary in appearance and in size in different cases. When it is possible to trace the cellsfrom the seat of origin to the deeper tissues they may be large, epithelial in appearance,and extend in prolongations that branch and ramify as in squamous-cell carcinoma,but differing in being pigmented and showing no tendency to cornify. The nearer the surface the cells are, the larger they are, and the more distinctlyepithelial they appear; the deeper into the tumor one extends the examination, the moreregular, more numerous and more sarcoma-like they become. In the secondary tumorsthe cells occur in uniform masses like sarcoma, but commonly deeply pigmented. It isnot impossible for the secondary metastatic tumors to be lacking in Fig. -Adeno-sarcoma of the breast. The usual loose periductal fibrillar tissue has become purelycellular in type. In most cases the cells are round in shape, but occasionally one finds spindle cellsalso deeply pigmented. We have found no references to the occurrence of such tumorsin the breast, however. The pigment is melanin. Cornil and Ranvier (Manuel dHist. Path., I, 331)in describing a case observed by them, state that the melanotic substance was contained,not in the connective tissue, but in the epithelial cells of the glandular acini. Here thepigment had evidently been secreted by the cells themselves. It is to be supposedthat glandular acini as used here means nests of tumor cells, and not acini of mammarytissue. VIII. Chloroma.—This pecuHar and rare tumor is Hke sarcoma in being purelycellular, and is characterized by the presence of certain lipochromes that give its tissuea bright green color on fresh se
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectbreast, bookyear1917
