Human PARP-1 (Poly(ADP-ribose)-Polymerase-1) bound to a DNA double strand break, molecular model. Human PARP-1 (Poly(ADP-ribose)-Polymerase-1) is a hi

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Human PARP-1 (Poly(ADP-ribose)-Polymerase-1) bound to a DNA double strand break, molecular model. Human PARP-1 (Poly(ADP-ribose)-Polymerase-1) is a highly conserved protein (113 kDa) that is strongly activated by DNA strand breaks, and participates in modulating DNA base excision repair, apoptosis, and necrosis. It includes a DNA-binding domain with 23 zinc finger motifs, and a poly(ADP-ribose) polymerase catalytic domain

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Size: 3750px × 5000px
Photo credit: © ALFRED PASIEKA/SCIENCE PHOTO LIBRARY / Alamy / Afripics
License: Licensed
Model Released: No

Keywords: 1, ageing, aging, brca1, brca2, break, cell, damage, dna, free, genome, hormesis, ionizing, mutation, nucleus, oxidants, oxidation, parp, parp-1, polyadp-ribose, polymerase, progeria, radiation, radicals, repair